The Chemical Profile of 7-Chloro-4-hydroxyquinoline-3-carboxylic Acid: CAS 86-47-5
Understanding the precise chemical identity and properties of intermediates is fundamental to successful chemical synthesis. 7-Chloro-4-hydroxyquinoline-3-carboxylic acid, bearing the CAS number 86-47-5, is a compound that merits close examination due to its significant role in various industrial applications, particularly as a pharmaceutical intermediate and a dyestuff intermediate.
The molecular formula for this compound is C10H6ClNO3, with a molecular weight of approximately 223.61 g/mol. Its structure features a quinoline ring system substituted with a chlorine atom at the 7-position, a hydroxyl group at the 4-position, and a carboxylic acid group at the 3-position. This unique arrangement of functional groups dictates its reactivity and utility in further chemical transformations.
Commonly found in a solid form, 7-Chloro-4-hydroxyquinoline-3-carboxylic acid typically presents as a white to pale brown powder or crystals. Its melting point is often cited as approximately 250 °C with decomposition, indicating its thermal stability under normal processing conditions. Information regarding its solubility varies, with some sources indicating slight solubility in solvents like DMSO and methanol, which is important for reaction planning.
The compound is also known by several synonyms, reflecting its importance and various nomenclature systems used in chemistry. These include 3-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-, 7-Chloro-4-Hydroxy-3-Carboxyquinoline, and 7-chloro-4-keto-1H-quinoline-3-carboxylic acid, among others. Familiarity with these synonyms is crucial for effective literature searches and cross-referencing information, especially when dealing with pharmaceutical raw materials or organic synthesis building blocks.
Storage conditions typically recommend keeping the compound in a cool, dry place within a tightly closed container, with adequate ventilation. This ensures the preservation of its quality and prevents degradation over time. For those involved in dyestuff intermediates manufacturing or broader fine chemical intermediate sourcing, a thorough understanding of these chemical details is indispensable.
In essence, the chemical profile of 7-Chloro-4-hydroxyquinoline-3-carboxylic acid provides the foundational knowledge required for its effective use in synthesis. Its properties make it a reliable and valuable intermediate for chemists and manufacturers worldwide.
The molecular formula for this compound is C10H6ClNO3, with a molecular weight of approximately 223.61 g/mol. Its structure features a quinoline ring system substituted with a chlorine atom at the 7-position, a hydroxyl group at the 4-position, and a carboxylic acid group at the 3-position. This unique arrangement of functional groups dictates its reactivity and utility in further chemical transformations.
Commonly found in a solid form, 7-Chloro-4-hydroxyquinoline-3-carboxylic acid typically presents as a white to pale brown powder or crystals. Its melting point is often cited as approximately 250 °C with decomposition, indicating its thermal stability under normal processing conditions. Information regarding its solubility varies, with some sources indicating slight solubility in solvents like DMSO and methanol, which is important for reaction planning.
The compound is also known by several synonyms, reflecting its importance and various nomenclature systems used in chemistry. These include 3-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-, 7-Chloro-4-Hydroxy-3-Carboxyquinoline, and 7-chloro-4-keto-1H-quinoline-3-carboxylic acid, among others. Familiarity with these synonyms is crucial for effective literature searches and cross-referencing information, especially when dealing with pharmaceutical raw materials or organic synthesis building blocks.
Storage conditions typically recommend keeping the compound in a cool, dry place within a tightly closed container, with adequate ventilation. This ensures the preservation of its quality and prevents degradation over time. For those involved in dyestuff intermediates manufacturing or broader fine chemical intermediate sourcing, a thorough understanding of these chemical details is indispensable.
In essence, the chemical profile of 7-Chloro-4-hydroxyquinoline-3-carboxylic acid provides the foundational knowledge required for its effective use in synthesis. Its properties make it a reliable and valuable intermediate for chemists and manufacturers worldwide.
Perspectives & Insights
Core Pioneer 24
“Information regarding its solubility varies, with some sources indicating slight solubility in solvents like DMSO and methanol, which is important for reaction planning.”
Silicon Explorer X
“The compound is also known by several synonyms, reflecting its importance and various nomenclature systems used in chemistry.”
Quantum Catalyst AI
“These include 3-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-, 7-Chloro-4-Hydroxy-3-Carboxyquinoline, and 7-chloro-4-keto-1H-quinoline-3-carboxylic acid, among others.”