The Chemical Properties and Uses of 2-Amino-4-chlorophenol (CAS 95-85-2)
Understanding the fundamental chemical properties and applications of an intermediate like 2-Amino-4-chlorophenol (CAS 95-85-2) is crucial for chemists, formulators, and procurement specialists. This compound, often referred to as 4-CAP, serves as a critical building block in several industrial processes, most notably in the synthesis of dyes. NINGBO INNO PHARMCHEM CO.,LTD. provides high-quality 4-CAP and offers insights into its technical profile.
Chemical Identity and Properties
Chemical Name: 2-Amino-4-chlorophenol
Synonyms: 4-Chloro-2-aminophenol, 4-CAP, C.I. 76525, C.I. Oxidation Base 18
CAS Number: 95-85-2
Molecular Formula: C6H6ClNO
Molecular Weight: 143.57 g/mol
Physical Characteristics:
2-Amino-4-chlorophenol typically appears as a pale orange to light brown crystalline solid. It has a melting point in the range of 136-141 °C. Its solubility in water is low, but it is generally soluble in organic solvents such as methanol, benzene, and acetone, as well as in acidic and alkaline solutions. The compound's stability under recommended storage conditions makes it amenable to industrial handling and processing.
Key Chemical Reactivity:
- Amino Group: The -NH2 group is basic and nucleophilic, allowing it to undergo reactions like acylation, alkylation, and importantly, diazotization. The diazotization of the amino group is a fundamental step in the synthesis of azo dyes.
- Hydroxyl Group: The phenolic -OH group imparts weakly acidic properties and can participate in etherification, esterification, and reactions typical of phenols, such as electrophilic aromatic substitution.
- Chlorine Atom: The chlorine substituent influences the electron density of the aromatic ring and can participate in nucleophilic aromatic substitution under specific, usually forcing, conditions.
Industrial Applications of 4-CAP
The primary application for 2-Amino-4-chlorophenol is as a key intermediate in the production of dyes and pigments. Its ability to form stable azo linkages makes it invaluable for creating a wide spectrum of colors used in the textile industry, printing inks, and other coloration applications. Researchers and manufacturers looking to purchase this compound for dye synthesis rely on its consistent quality and reactivity to achieve desired shades and performance characteristics.
Beyond dyes, 4-CAP can also serve as a building block in the synthesis of other fine chemicals, including potential intermediates for pharmaceuticals or agrochemicals, where its specific functional group arrangement can be advantageous. For those requiring a reliable source of 2-Amino-4-chlorophenol, NINGBO INNO PHARMCHEM CO.,LTD. offers high-purity material, ensuring that your industrial and research needs are met with precision and consistency.
Perspectives & Insights
Future Origin 2025
“Key Chemical Reactivity: Amino Group: The -NH2 group is basic and nucleophilic, allowing it to undergo reactions like acylation, alkylation, and importantly, diazotization.”
Core Analyst 01
“The diazotization of the amino group is a fundamental step in the synthesis of azo dyes.”
Silicon Seeker One
“Hydroxyl Group: The phenolic -OH group imparts weakly acidic properties and can participate in etherification, esterification, and reactions typical of phenols, such as electrophilic aromatic substitution.”