The Chemical Synthesis of N-Phenyldiethanolamine (CAS 120-07-0)
For chemists, formulators, and procurement managers, understanding the synthesis and production methods of chemical intermediates is key to ensuring quality and reliability. N-Phenyldiethanolamine (CAS 120-07-0) is a significant organic compound, primarily used as an intermediate in the pharmaceutical and dye industries. As a prominent N-Phenyldiethanolamine manufacturer, we focus on efficient and quality-driven synthesis processes to meet market demands.
The most common method for synthesizing N-Phenyldiethanolamine involves the reaction between aniline and ethylene oxide. This reaction, typically carried out under controlled conditions, leads to the formation of the target molecule. The stoichiometry and reaction parameters, such as temperature, pressure, and catalyst selection, are critical for achieving high yields and purity, which is often specified at 98% minimum assay. The product typically presents as a slight yellow crystal.
Understanding the Synthesis Process:
- Aniline and Ethylene Oxide Reaction: The core synthesis route involves the addition of ethylene oxide to aniline. This process results in the gradual addition of hydroxyethyl groups to the nitrogen atom of aniline, forming N-Phenyldiethanolamine. Careful control of the ethylene oxide addition is crucial to minimize side reactions and the formation of unwanted by-products.
- Purification: Following the initial synthesis, purification steps are essential to achieve the desired high purity (e.g., 98% min). These may include recrystallization, distillation, or other separation techniques to remove unreacted starting materials, by-products, and impurities.
- Quality Control: Rigorous quality control measures are implemented throughout the production process. Analytical techniques such as Gas Chromatography (GC) are used to verify the assay and identify any residual impurities, ensuring that the final product meets stringent industry specifications for use as a pharmaceutical or dye intermediate.
For those looking to buy N-Phenyldiethanolamine, understanding these production aspects highlights the importance of partnering with experienced manufacturers. A reliable N-Phenyldiethanolamine supplier will not only offer competitive N-Phenyldiethanolamine price points but also guarantee the consistency and quality derived from well-established synthesis and purification protocols.
The consistent availability of high-purity N-Phenyldiethanolamine is crucial for downstream industries. Whether it’s for developing new pharmaceuticals or creating advanced dyes, the quality of this intermediate directly impacts the final product's performance and safety. Engaging with a reputable N-Phenyldiethanolamine manufacturer ensures you receive a product that has been synthesized with precision and care.
Perspectives & Insights
Data Seeker X
“The most common method for synthesizing N-Phenyldiethanolamine involves the reaction between aniline and ethylene oxide.”
Chem Reader AI
“This reaction, typically carried out under controlled conditions, leads to the formation of the target molecule.”
Agile Vision 2025
“The stoichiometry and reaction parameters, such as temperature, pressure, and catalyst selection, are critical for achieving high yields and purity, which is often specified at 98% minimum assay.”