Exploring the Chemistry of 2-Amino-4-chloro-5-methylbenzenesulfonic Acid: Properties and Synthesis Pathways
Understanding the fundamental chemistry of vital industrial compounds is key to unlocking their full potential. NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing such essential chemical intermediates, including the notable 2B Acid, scientifically known as 2-Amino-4-chloro-5-methylbenzenesulfonic acid (CAS No. 88-51-7).
The chemical structure of 2B Acid is a substituted benzenesulfonic acid derivative. It features a benzene ring with an amino group (-NH2) at position 2, a chlorine atom (-Cl) at position 4, and a methyl group (-CH3) at position 5, alongside a sulfonic acid group (-SO3H). This specific arrangement of functional groups dictates its reactivity and properties, making it an ideal intermediate for organic synthesis, particularly in the creation of azo pigments.
Key chemical properties of 2B Acid include its appearance as a white to off-white or slightly rose-red crystalline powder. Its solubility is noteworthy: it is sparingly soluble in cold water but shows better solubility in hot water and in dilute alkaline solutions. This solubility profile is critical for its use in various chemical reactions, as it influences reaction rates and product isolation methods. The compound has a molecular weight of 221.66 g/mol and an EINECS number of 201-837-6.
The synthesis of 2B Acid typically involves multiple steps starting from more basic organic compounds. Common synthetic routes often begin with the nitration of a suitable toluene derivative, followed by chlorination, reduction of the nitro group to an amino group, and finally sulfonation. For instance, a common pathway might involve the sulfonation of 3-chloro-4-methylaniline. Precise control over reaction conditions, such as temperature, pressure, and the choice of sulfonating agent (e.g., sulfuric acid or oleum), is essential to ensure the regioselectivity of the sulfonation and to achieve high yields and purity of the desired 2-Amino-4-chloro-5-methylbenzenesulfonic acid.
The importance of 2B Acid extends to its application as an intermediate for synthesizing various organic pigments. The amino group can be readily diazotized, and the resulting diazonium salt can then undergo azo coupling reactions with suitable coupling components. This process forms the basis for many vibrant organic pigments, particularly those in the red and related color ranges, such as those used in inks, coatings, and plastics. The intrinsic properties of the 2B Acid molecule contribute to the stability and color characteristics of the final pigment.
For businesses looking to buy 2B Acid, understanding these chemical fundamentals ensures informed purchasing decisions. NINGBO INNO PHARMCHEM CO.,LTD. provides high-quality 2-Amino-4-chloro-5-methylbenzenesulfonic acid, adhering to strict purity standards. Our expertise in fine chemical synthesis ensures that our clients receive an intermediate that is optimized for their manufacturing processes, contributing to the production of superior colorants.
Perspectives & Insights
Core Pioneer 24
“The chemical structure of 2B Acid is a substituted benzenesulfonic acid derivative.”
Silicon Explorer X
“It features a benzene ring with an amino group (-NH2) at position 2, a chlorine atom (-Cl) at position 4, and a methyl group (-CH3) at position 5, alongside a sulfonic acid group (-SO3H).”
Quantum Catalyst AI
“This specific arrangement of functional groups dictates its reactivity and properties, making it an ideal intermediate for organic synthesis, particularly in the creation of azo pigments.”