In the vast landscape of chemical compounds, certain molecules stand out for their versatility and importance across multiple industrial sectors. 3-Chloro-4-fluorobenzaldehyde (CAS: 34328-61-5) is one such compound, a key aromatic aldehyde valued for its unique chemical properties and broad applicability in organic synthesis, pharmaceuticals, and agrochemicals.

Understanding the Chemical Profile

3-Chloro-4-fluorobenzaldehyde is a derivative of benzaldehyde, characterized by the presence of a chlorine atom at the 3-position and a fluorine atom at the 4-position of the benzene ring. Its molecular formula is C7H4ClFO, with a molecular weight of approximately 158.56 g/mol. Key physical and chemical properties include:

  • Appearance: Typically described as a colorless to light yellow crystalline powder or solid.
  • Melting Point: Ranges from 24°C to 30°C, indicating it can be a low-melting solid or even liquid at slightly elevated room temperatures.
  • Boiling Point: Approximately 66-72°C at reduced pressure (e.g., 2 mmHg), and higher at atmospheric pressure.
  • Purity: Commonly available with a purity of ≥96% or ≥99.0% for higher-grade applications.
  • Reactivity: The aldehyde group is highly reactive, undergoing typical aldehyde reactions. The halogen substituents influence the electron distribution of the aromatic ring, impacting reactivity in electrophilic and nucleophilic substitution reactions.

Industrial Applications and Significance

The utility of 3-Chloro-4-fluorobenzaldehyde spans several critical industries:

  • Organic Synthesis: It serves as a fundamental building block for synthesizing a myriad of complex organic molecules. Its dual functionality (aldehyde and halogenated aromatic ring) allows for diverse synthetic strategies, making it invaluable in research and development laboratories worldwide.
  • Pharmaceutical Intermediates: This compound is a vital precursor in the synthesis of various Active Pharmaceutical Ingredients (APIs). Its structure is often modified to create drugs with specific therapeutic effects, including anti-inflammatory agents and potential anti-cancer compounds.
  • Agrochemical Synthesis: It plays a role in the manufacturing of pesticides and herbicides. The incorporation of halogen atoms can enhance the efficacy and stability of these agricultural chemicals, contributing to improved crop yields and protection.
  • Material Science: In some specialized applications, it can be used in the development of advanced materials where specific chemical or electronic properties are required.

Sourcing from a Reliable Manufacturer

For professionals requiring 3-Chloro-4-fluorobenzaldehyde, sourcing from a reputable manufacturer and supplier is crucial. As a dedicated producer and distributor, we offer high-purity 3-Chloro-4-fluorobenzaldehyde, ensuring that your synthesis and production processes benefit from consistent quality and reliable supply. We cater to various needs, from research quantities to bulk industrial orders. We invite you to request a quote and discover how our commitment to quality and competitive pricing can support your chemical needs. Our extensive experience as a chemical supplier ensures that your procurement process is efficient and reliable.

3-Chloro-4-fluorobenzaldehyde continues to be a pivotal compound, enabling advancements across chemistry and related industries.