For research scientists and process chemists, a thorough understanding of a chemical intermediate's properties and synthesis is fundamental to successful application and optimization. Acetoacet-2,5-Dimethoxyanilide (CAS: 6375-27-5) is a prime example of such a compound, playing a critical role in the synthesis of various organic compounds, most notably pigments. This article delves into its key technical aspects, providing valuable information for professionals in the field.

Chemical Profile and Properties

Acetoacet-2,5-Dimethoxyanilide, chemically known as N-(2,5-dimethoxyphenyl)-3-oxobutanamide, possesses the molecular formula C12H15NO4 and a molecular weight of approximately 237.25 g/mol. Its structural features, including the acetamide and dimethoxyphenyl groups, dictate its reactivity and suitability for specific chemical transformations.

Key physical and chemical properties often cited include:

  • Appearance: Typically a White crystal powder.
  • Purity: Commonly specified as ≥99.0%.
  • Melting Point: Reported between 67-68 °C.
  • Boiling Point: Around 410 °C at 760 mmHg (predicted).
  • Density: Approximately 1.182 g/cm³ (predicted).
  • Solubility: Soluble in methanol and other organic solvents.

These properties are crucial for R&D scientists when designing reaction conditions, selecting solvents, and determining appropriate handling and storage procedures.

Synthesis Pathways and Applications

The synthesis of Acetoacet-2,5-Dimethoxyanilide typically involves the acetoacetylation of 2,5-dimethoxyaniline. Common methods utilize reagents like diketene or ethyl acetoacetate under controlled conditions. The efficiency and yield of this process are vital for manufacturers looking to supply this intermediate reliably.

Its primary application lies in the pigment industry, where it functions as a coupling component for synthesizing azo pigments. Specifically, it is a precursor for C.I. Pigment Yellow 87, a compound valued for its color brilliance and stability in various applications, from inks to coatings.

For companies looking to buy Acetoacet-2,5-Dimethoxyanilide, understanding these technical details ensures that the sourced material will perform as expected in their synthesis processes. NINGBO INNO PHARMCHEM CO.,LTD., as a specialized chemical manufacturer, provides this intermediate with consistent specifications, supporting the research and development efforts of our clients. If you require Acetoacet-2,5-Dimethoxyanilide for your next synthesis project, contact us to learn more about our product quality and availability.