The Technical Profile of 3-Amino-4-methoxybenzanilide (CAS 120-35-4)
For chemical researchers, product formulators, and procurement specialists, a deep understanding of a compound's technical profile is indispensable for successful application and sourcing. 3-Amino-4-methoxybenzanilide (CAS 120-35-4), a key intermediate in the synthesis of dyes and pigments, possesses a distinct set of chemical and physical properties that dictate its utility.
Chemical Identity and Nomenclature
The compound is formally known as 3-Amino-4-methoxybenzanilide. Its CAS Registry Number, 120-35-4, is a unique identifier crucial for accurate information retrieval and trade. Common synonyms found in literature and supplier catalogs include AMAN, AMBA, Fast Red KD Base, and 3-Amino-p-anisilide, among others. The IUPAC name is 3-amino-4-methoxy-N-phenylbenzamide.
Molecular Structure and Formula
The molecular formula of 3-Amino-4-methoxybenzanilide is C14H14N2O2. This formula indicates the presence of carbon, hydrogen, nitrogen, and oxygen atoms in specific ratios. Its molecular weight is approximately 242.27 g/mol. The structure features a benzanilide core with an amino group (-NH2) at the 3-position and a methoxy group (-OCH3) at the 4-position on one of the phenyl rings, and a phenyl group attached to the amide nitrogen.
Physical Properties
In its pure form, 3-Amino-4-methoxybenzanilide typically presents as a white to off-white solid. This solid state is consistent with its melting point, which is generally reported to be in the range of 154-156°C. Such a melting point suggests moderate thermal stability under typical ambient conditions. Its solubility is often described as slight in polar organic solvents like DMSO and methanol, indicating it is not highly soluble in water or common non-polar solvents. The density is approximately 1.1338 g/cm³ (estimated).
Key Spectral and Analytical Data
While detailed spectral data (like NMR, IR, Mass Spectrometry) is essential for R&D and quality control, they are beyond the scope of this overview. However, its molecular structure and functional groups allow for characteristic spectral signatures. For example, the presence of the amino group (-NH2) and the amide proton (-NH-) are observable in NMR spectra.
Safety Information
Safety data sheets (SDS) classify 3-Amino-4-methoxybenzanilide as an IRRITANT, with hazard statements such as H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Precautionary statements (e.g., P261, P305+P351+P338) advise on proper handling, ventilation, and personal protective equipment. It is critical for all users to consult the full SDS before handling.
Applications and Significance
As a fine chemical intermediate, its primary significance lies in its role as a diazo component for azoic dyes and pigments. The precise arrangement of functional groups makes it a reliable precursor for creating vibrant and stable colors used in textiles, inks, and paints. Understanding these technical specifications is vital for R&D scientists and product formulators when considering its use in new product development or process optimization. For procurement managers, confirming these technical specifications from reliable manufacturers in China is key to ensuring product efficacy and consistency.
Perspectives & Insights
Molecule Vision 7
“However, its molecular structure and functional groups allow for characteristic spectral signatures.”
Alpha Origin 24
“For example, the presence of the amino group (-NH2) and the amide proton (-NH-) are observable in NMR spectra.”
Future Analyst X
“Safety Information Safety data sheets (SDS) classify 3-Amino-4-methoxybenzanilide as an IRRITANT, with hazard statements such as H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation).”