For chemical industry professionals, staying abreast of key intermediates is vital for strategic sourcing and product development. 2,3,6-Trimethylphenol (CAS 2416-94-6), an aromatic compound with significant industrial applications, warrants close attention. This article provides a comprehensive overview of its chemical properties, common synthesis methods, and current market trends, offering valuable insights for procurement managers and R&D scientists seeking to buy 2,3,6-trimethylphenol.

Chemical Profile of 2,3,6-Trimethylphenol

2,3,6-Trimethylphenol, also known by synonyms such as 3-Hydroxypseudocumene, is an organic chemical with the molecular formula C9H12O. Key physical and chemical properties include:

  • Appearance: White to light yellow crystalline solid.
  • Purity: Typically available at ≥99.0% purity, with pharmaceutical grades also offered.
  • Melting Point: Approximately 60-63°C.
  • Boiling Point: Around 232-234°C.
  • Flash Point: 110°C (Closed Cup).
  • Stability: Stable under normal conditions when stored properly (sealed containers, inert atmosphere, <30°C).
  • Applications: Primarily used as a key intermediate in the synthesis of Vitamin E (tocopherol). It also finds use in the production of phenolic resins, antioxidants, pharmaceuticals, and fragrance intermediates.

The sterically hindered phenolic structure of 2,3,6-trimethylphenol is crucial to its utility, enabling specific reactions and conferring desirable properties to downstream products.

Synthesis Routes for 2,3,6-Trimethylphenol

While the detailed synthesis pathways can be complex, industrial production of 2,3,6-trimethylphenol often involves the alkylation of phenols or related aromatic compounds. More recently, research has focused on optimizing the conversion of TMP into Vitamin E intermediates, as discussed previously, often involving catalytic oxidation with air. Understanding these synthesis methodologies can help buyers appreciate the quality and potential variations in the product they source.

Market Trends and Sourcing Considerations

The market for 2,3,6-trimethylphenol is primarily driven by the demand for Vitamin E, which is influenced by trends in the food, feed, cosmetic, and pharmaceutical industries. Growth in these sectors directly impacts the need for TMP.

When planning to buy 2,3,6-trimethylphenol, B2B professionals should consider:

  • Global Demand for Vitamin E: Fluctuations in Vitamin E market demand will affect TMP availability and pricing.
  • Regulatory Landscape: Compliance with chemical regulations in different regions is crucial for importers.
  • Supplier Reliability: Securing a stable supply requires partnering with established manufacturers. Identifying a trusted 2,3,6-trimethylphenol manufacturer, particularly from regions like China, is essential.
  • Pricing Dynamics: Keep informed about the current 2,3,6-trimethylphenol price, as market fluctuations can occur.
  • Quality Control: Always verify the purity and specifications through Certificates of Analysis (COA) from suppliers like NINGBO INNO PHARMCHEM CO.,LTD.

By staying informed about the properties, synthesis, and market dynamics of 2,3,6-trimethylphenol, businesses can make more strategic procurement decisions. Accessing high-quality intermediates from reliable suppliers is key to maintaining efficient production and achieving product excellence.