Beyond its industrial applications, 4-Dodecylaniline (CAS 104-42-7) has garnered scientific interest for its intriguing biological activities, particularly its antioxidant and cytoprotective effects. This aromatic amine, with its distinct dodecyl chain, exhibits properties that can shield cells from damage caused by oxidative stress. Understanding these biological mechanisms can open new avenues for its application in fields ranging from pharmaceuticals to specialized research chemicals.

Oxidative stress, a cellular imbalance caused by an excess of reactive oxygen species (ROS), is implicated in numerous diseases and cellular dysfunctions. Research has indicated that 4-Dodecylaniline can effectively combat this stress. In studies involving cell models, such as HT22 cells, the compound has shown a remarkable ability to protect cells against damage induced by various oxidants like glutamate, hydrogen peroxide, and tert-butyl hydroperoxide. The observed half-maximal effective concentrations (EC50) highlight its potency as a cellular protector.

The proposed mechanisms behind these cytoprotective effects are multifaceted. One key action appears to be the inhibition of lipid peroxidation. The long dodecyl chain may facilitate interaction with cell membranes, stabilizing them and preventing the chain reactions initiated by free radicals. Furthermore, 4-Dodecylaniline has been shown to reduce the intracellular accumulation of peroxides, a direct measure of its ability to mitigate oxidative damage and maintain cellular integrity. These actions are critical for preserving cell viability and function, especially in sensitive tissues like neurons.

For researchers investigating neuroprotection, cellular health, or developing novel therapeutic agents, access to compounds with such protective properties is invaluable. NINGBO INNO PHARMCHEM CO., LTD., as a dedicated manufacturer and supplier of specialty chemicals, provides high-quality 4-Dodecylaniline that meets the stringent purity requirements for biological and chemical research. Our consistent product quality ensures that experimental results are reliable and reproducible.

The exploration of 4-Dodecylaniline's biological activity also extends to its potential use in drug delivery systems. Its chemical structure could be leveraged to create responsive carriers that release therapeutic agents under specific biological conditions, such as in tumor microenvironments. This area of research is rapidly evolving, and the availability of well-characterized intermediates is key to progress.

For R&D scientists and procurement managers looking for compounds with demonstrated antioxidant and cytoprotective properties, 4-Dodecylaniline presents a compelling option. We invite you to contact NINGBO INNO PHARMCHEM CO., LTD. to discuss your specific research needs, inquire about pricing for bulk orders, or to request a sample. Partner with us to access high-quality chemical intermediates that can drive your scientific discoveries and product development forward.