3-Nitro-N-(2-Hydroxypropyl)-4-Aminophenol: A Pharmaceutical Synthesis Intermediate
In the realm of pharmaceutical R&D and manufacturing, the quality and availability of chemical intermediates are paramount. 3-Nitro-N-(2-Hydroxypropyl)-4-Aminophenol (CAS No: 92952-81-3) is gaining recognition as a versatile intermediate for synthesizing various active pharmaceutical ingredients (APIs). For research scientists and procurement specialists, understanding how to effectively buy this compound from a reliable manufacturer is key to accelerating drug development pipelines.
Chemical Properties and Synthesis for Pharmaceutical Use: The compound's structure, characterized by its nitro group, amino group, and a hydroxypropyl side chain, offers multiple reactive sites essential for complex organic synthesis. Typically supplied with a purity of ≥98.0% by HPLC, it meets the stringent demands of pharmaceutical research. Its synthesis involves carefully controlled chemical reactions, ensuring minimal impurities that could affect subsequent reactions or the final API. A deep understanding of its physical properties, such as its melting point (108-109°C) and solubility, is crucial for process optimization.
Applications in Drug Discovery: The functional groups present in 3-Nitro-N-(2-Hydroxypropyl)-4-Aminophenol allow for diverse chemical transformations. Researchers can modify the nitro group through reduction to an amine, or functionalize the hydroxyl and secondary amine groups. These modifications can lead to the development of novel therapeutic agents targeting a range of diseases. As a chemical intermediate, it serves as a critical building block, enabling the construction of more complex molecular architectures required for new drug candidates. Procuring this chemical reliably is a foundational step in many pharmaceutical research projects.
Sourcing Strategy: Manufacturer vs. Distributor: When seeking to purchase 3-Nitro-N-(2-Hydroxypropyl)-4-Aminophenol for pharmaceutical applications, partnering directly with a reputable manufacturer offers distinct advantages. Direct sourcing from a chemical company in China, for instance, often ensures better prices, greater transparency in quality control, and a more secure supply chain. It is vital to work with suppliers who can provide comprehensive documentation, including detailed CoAs and safety data sheets (SDS), which are critical for regulatory compliance in the pharmaceutical industry. NINGBO INNO PHARMCHEM CO.,LTD. is positioned to be your trusted partner, offering both high-quality intermediates and robust support.
Beyond Pharmaceuticals: Cosmetic Industry Relevance: While its pharmaceutical applications are significant, it is also well-known as a hair dye intermediate. This broad utility highlights the compound's chemical versatility. For companies operating in both sectors, consolidating procurement can lead to greater efficiency. By choosing a supplier that can cater to diverse needs, businesses can streamline their operations and focus on innovation, confident in the consistent quality and availability of essential chemical building blocks.
Perspectives & Insights
Bio Analyst 88
“3-Nitro-N-(2-Hydroxypropyl)-4-Aminophenol (CAS No: 92952-81-3) is gaining recognition as a versatile intermediate for synthesizing various active pharmaceutical ingredients (APIs).”
Nano Seeker Pro
“For research scientists and procurement specialists, understanding how to effectively buy this compound from a reliable manufacturer is key to accelerating drug development pipelines.”
Data Reader 7
“Chemical Properties and Synthesis for Pharmaceutical Use: The compound's structure, characterized by its nitro group, amino group, and a hydroxypropyl side chain, offers multiple reactive sites essential for complex organic synthesis.”