The Endogenous Role of Oleamide: From Neurobiology to Potential Therapies
Oleamide, chemically known as 9-Octadecenamide (CAS 301-02-0), is more than just an industrial chemical; it is an endogenous fatty acid amide with significant implications in neurobiology and potential therapeutic applications. NINGBO INNO PHARMCHEM CO.,LTD. is keenly interested in the biological functions of this compound, driven by its natural occurrence and its interaction with crucial physiological pathways.
First identified in human plasma, Oleamide has been found to accumulate in the cerebrospinal fluid (CSF) during sleep deprivation. This observation led to early research suggesting its role in sleep regulation. Subsequent studies have confirmed that Oleamide can indeed induce sleep in animal models. The complex mechanisms behind this effect involve interactions with various neurotransmitter systems, including the serotonin system and the endocannabinoid system. Specifically, Oleamide has been shown to be an agonist for the cannabinoid CB1 receptor, a key player in regulating mood, appetite, and pain perception. Additionally, its modulatory effects on serotonin receptors (5-HT2A, 5-HT2C, and 5-HT1A) suggest a broad impact on neurological function.
The potential therapeutic applications of Oleamide are vast. Its ability to influence sleep patterns makes it a candidate for treating insomnia and other sleep disorders. Furthermore, its interactions with mood-regulating neurotransmitters suggest potential benefits for mood disorders and anxiety. Research into Oleamide's effects on neuroinflammation and its structural similarity to anandamide, another key endocannabinoid, opens avenues for exploring its role in managing neurological conditions. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying high-purity Oleamide for research, enabling scientists to further unravel its biological activities.
While its primary uses have historically been in industrial sectors as a slip agent and lubricant, the growing body of scientific evidence highlights Oleamide's importance in biological systems. The research into its buy/purchase options for scientific investigation is critical for advancing our understanding of its neurobiological roles. By providing access to quality Oleamide, NINGBO INNO PHARMCHEM CO.,LTD. supports the scientific community in exploring the full therapeutic potential of this fascinating molecule, from promoting restful sleep to modulating complex neurological pathways.
Perspectives & Insights
Core Pioneer 24
“Additionally, its modulatory effects on serotonin receptors (5-HT2A, 5-HT2C, and 5-HT1A) suggest a broad impact on neurological function.”
Silicon Explorer X
“Its ability to influence sleep patterns makes it a candidate for treating insomnia and other sleep disorders.”
Quantum Catalyst AI
“Furthermore, its interactions with mood-regulating neurotransmitters suggest potential benefits for mood disorders and anxiety.”