Ethyl 3-methyl-3-phenylglycidate (CAS 77-83-8), often recognized by its popular moniker 'Strawberry Aldehyde,' is a fascinating chemical compound with a significant presence in multiple industries. Its distinct molecular structure, featuring an epoxide and an ester functional group, endows it with unique chemical properties that drive its utility in flavor, fragrance, and pharmaceutical applications.

Chemically, this compound is a glycidic ester, typically presenting as a colorless to pale yellow liquid. While its common name suggests an aldehyde, it is structurally different. A key characteristic is its intense, sweet, and fruity aroma that strongly mimics that of strawberries, making it a cornerstone ingredient for artificial strawberry flavors. This aroma is often described as being more refined and potent than other strawberry scent compounds.

The reactivity of the epoxide ring makes Ethyl 3-methyl-3-phenylglycidate a valuable intermediate in organic synthesis. It readily undergoes ring-opening reactions, allowing chemists to build more complex molecules. This is particularly important in the pharmaceutical industry, where it serves as a building block for synthesizing various APIs and complex organic compounds. Its ability to participate in stereoselective reactions is also of great interest for creating specific enantiomers required in drug development.

In the flavor and fragrance sector, its application is widespread. It is used at low concentrations to impart a realistic strawberry note in candies, beverages, perfumes, and cosmetics. The compound is generally stable under typical storage conditions, though it is noted to be unstable in alkaline environments.

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