The sensory world of flavors and fragrances is built upon a foundation of complex organic chemistry. Among the many molecules that contribute to our olfactory and gustatory perceptions, thiazole derivatives hold a special place. 2-Isobutylthiazole, identified by its CAS number 18640-74-9, is a prime example of such a compound, offering a distinctive profile that appeals to both flavorists and perfumers. Understanding its chemical structure and properties is key to appreciating its value as a 'flavor and fragrance intermediate'.

Chemically, 2-Isobutylthiazole is a heterocyclic organic compound belonging to the thiazole family. Its structure features a five-membered ring containing both sulfur and nitrogen atoms, with an isobutyl group attached at the second position of the ring. This specific arrangement of atoms is responsible for its unique sensory attributes. The 'isobutyl group' provides a degree of lipophilicity, influencing its solubility and interaction with olfactory and taste receptors, while the thiazole ring contributes to its characteristic aroma and flavor notes.

While the raw material is described as a 'colorless to light yellow liquid', its chemical identity is defined by its molecular formula C7H11NS and a molecular weight of approximately 141.234 g/mol. Key physical properties like boiling point (around 182.7 °C at 760 mmHg) and flash point (around 57.8 °C) are critical data points for manufacturers and formulators for safe handling, storage, and processing. The specifications often emphasize a high assay, typically ≥99.0%, ensuring the integrity of its sensory contribution.

The synthesis of 2-Isobutylthiazole generally involves cyclization reactions. One common pathway described in chemical literature involves reacting aliphatic amides with alpha,beta-dihalogenated ethers or related precursors. For the industrial 'manufacturer of 2-isobutylthiazole', optimizing these synthesis routes is crucial to achieve high yields, minimize by-products, and ensure cost-effectiveness. This focus on efficient 'chemical synthesis' is what allows for the consistent availability of this compound at competitive 'prices'.

As a 'chemical intermediate', 2-Isobutylthiazole is not only used directly for its sensory properties but can also serve as a building block for more complex molecules. Its reactivity, influenced by the thiazole ring and the attached functional group, makes it a valuable starting material for further chemical transformations in research and development settings. For scientists looking to 'purchase 2-isobutylthiazole' for such synthetic purposes, understanding its chemical behavior is as important as knowing its sensory profile.