Understanding the Chemistry of Guaiacol (2-Methoxyphenol)
Guaiacol, chemically known as 2-Methoxyphenol, is an aromatic organic compound that holds significant importance in the field of chemistry. Its structure, a benzene ring substituted with both a hydroxyl (-OH) and a methoxy (-OCH3) group at adjacent positions (ortho), dictates its reactivity and wide-ranging applications. For chemists, researchers, and industrial buyers, a thorough understanding of Guaiacol's chemistry is fundamental.
The molecular formula for Guaiacol is C7H8O2, and it has a molar mass of 124.139 g/mol. Physically, pure Guaiacol appears as a colorless oil or crystalline solid with a melting point between 26-29 °C. This property means it can exist in either state depending on ambient temperature. Its boiling point is around 204-206 °C, and it has a density of approximately 1.112 g/cm³. These physical characteristics are vital for handling, storage, and process design in industrial settings. The solubility of Guaiacol in water is about 23.3 g/L at 25 °C, indicating moderate water solubility due to the polar hydroxyl group.
The chemical reactivity of Guaiacol is influenced by its phenolic hydroxyl group and the activating methoxy group on the aromatic ring. The hydroxyl group imparts weakly acidic properties and is susceptible to etherification and esterification. The benzene ring itself can undergo electrophilic aromatic substitution reactions, with the directing effects of the hydroxyl and methoxy groups influencing the position of new substituents. This reactivity makes Guaiacol an excellent starting material for synthesizing a vast array of organic compounds.
Industrially, Guaiacol is primarily produced through the methylation of catechol (1,2-dihydroxybenzene). This chemical synthesis route is optimized by manufacturers to achieve high purity, often exceeding 99.0% assay. NINGBO INNO PHARMCHEM CO.,LTD. employs advanced synthetic techniques to produce high-quality Guaiacol, ensuring it meets the demanding specifications of various industries. As a dedicated chemical supplier, we provide detailed product specifications and technical data to our clients, facilitating informed purchasing decisions. When you buy Guaiacol, understanding its synthesis and purity is key.
The utility of Guaiacol as a chemical intermediate is perhaps its most significant contribution. It is a crucial precursor in the production of vanillin, a vital component in the flavor and fragrance industry. Furthermore, Guaiacol derivatives find applications in pharmaceuticals, agrochemicals, and materials science. For researchers exploring new synthetic pathways or manufacturers requiring a reliable building block, Guaiacol offers significant versatility. We encourage chemists to consider purchasing our 2-methoxyphenol for their synthesis projects, confident in its quality and availability.
In summary, the chemistry of Guaiacol (2-Methoxyphenol) is rich and diverse, underpinning its importance in numerous industrial and research applications. Its physical properties, reactivity, and synthesis methods are critical aspects for any professional working with this compound. NINGBO INNO PHARMCHEM CO.,LTD. is your dependable source for high-purity Guaiacol, supporting your chemical endeavors with quality products and expert service.
Perspectives & Insights
Logic Thinker AI
“We encourage chemists to consider purchasing our 2-methoxyphenol for their synthesis projects, confident in its quality and availability.”
Molecule Spark 2025
“In summary, the chemistry of Guaiacol (2-Methoxyphenol) is rich and diverse, underpinning its importance in numerous industrial and research applications.”
Alpha Pioneer 01
“Its physical properties, reactivity, and synthesis methods are critical aspects for any professional working with this compound.”