Coumarin, identified by CAS number 91-64-5, is a fascinating aromatic organic compound with a significant presence in both the natural world and industrial applications. Its chemical structure, belonging to the benzopyrone class, contributes to its characteristic sweet, hay-like aroma, making it highly valued in the fragrance industry. However, its utility extends deeply into the pharmaceutical sector, primarily as a foundational molecule for synthesizing powerful anticoagulant medications.

From a chemical perspective, Coumarin typically presents as white crystals with a distinct odor. Its solubility profile is noteworthy: it dissolves readily in organic solvents like alcohol and oils but shows limited solubility in water. This property influences its formulation in various products. With a melting point around 69°C and a boiling point near 297°C, it demonstrates moderate thermal stability, crucial for processing and storage. Manufacturers often adhere to strict purity standards, ensuring an assay of 99% or higher, with many offering grades that meet stringent USP, BP, EP, and FCC specifications.

The pharmaceutical significance of Coumarin is profound. It acts as a precursor in the synthesis of synthetic anticoagulants, the most famous being warfarin (marketed as Coumadin), which is structurally derived from coumarin and used to prevent blood clots. This makes Coumarin an indispensable intermediate for pharmaceutical companies. The ability to reliably purchase high-purity Coumarin from a reputable manufacturer is critical for the consistent production of these life-saving drugs.

When sourcing Coumarin for pharmaceutical applications, rigorous quality control and supply chain reliability are non-negotiable. Buyers should look for manufacturers who can provide comprehensive documentation, including detailed specifications, safety data sheets (SDS), and certificates of origin. Engaging with suppliers who specialize in fine chemical intermediates, particularly those with a strong presence in manufacturing hubs like China, can offer both quality assurance and competitive pricing.

For researchers and manufacturers investigating new therapeutic applications or requiring a dependable supply of this vital chemical, understanding its properties and sourcing channels is key. Whether you are developing new fragrances or synthesizing critical pharmaceuticals, securing a high-quality source for Coumarin ensures the efficacy and safety of your end products. Contacting a trusted supplier for pricing and availability is the next step in leveraging this versatile compound.