In the intricate world of pharmaceutical manufacturing, the quality and consistency of raw materials are non-negotiable. 2-Methyl-1-Butanol (CAS 137-32-6) stands out as a pivotal pharmaceutical intermediate, indispensable for the synthesis of numerous Active Pharmaceutical Ingredients (APIs). For R&D scientists and procurement specialists, understanding its properties and securing a reliable supply from a trusted manufacturer is key to successful drug development and production.

Chemical Profile of 2-Methyl-1-Butanol

2-Methyl-1-Butanol, a branched primary alcohol, is characterized by its high purity, often exceeding 99%. Its chemical formula, C5H12O, and CAS number 137-32-6 are well-documented. Its physical state as a colorless liquid with a moderate boiling point (around 130°C) and good solubility in organic solvents makes it a practical choice for various synthetic pathways.

Applications in Pharmaceutical Synthesis

The utility of 2-Methyl-1-Butanol in pharmaceutical synthesis is multifaceted:

  • As a Solvent: Its solvent properties facilitate reactions, improve solubility of reactants, and aid in purification processes.
  • As a Reactant/Intermediate: It participates directly in synthetic reactions, forming carbon-carbon bonds or undergoing functional group transformations to build complex molecular structures. For instance, it can be used in the esterification or etherification processes common in API manufacturing.
  • In Chirality: While the CAS 137-32-6 refers to the racemic mixture (DL-2-Methyl-1-Butanol), enantiomerically pure forms of related amyl alcohols are critical in chiral synthesis, highlighting the importance of specific isomers in pharmaceutical research.

Sourcing Considerations for Pharmaceutical Grade 2-Methyl-1-Butanol

When procuring 2-Methyl-1-Butanol for pharmaceutical applications, it is imperative to focus on:

  • Purity and Impurity Profiling: Pharmaceutical grade materials demand exceptionally high purity and well-controlled impurity profiles. A reputable supplier in China will provide detailed analytical data to meet these stringent requirements.
  • Regulatory Compliance: Ensure the material complies with relevant pharmaceutical regulations (e.g., GMP standards where applicable).
  • Batch-to-Batch Consistency: Reliable synthesis and quality control from the manufacturer are crucial for consistent API production.
  • Supply Chain Stability: A stable supply chain is essential to avoid disruptions in drug manufacturing. Choosing a reliable supplier ensures continuity.

Why Choose Us for Your Pharmaceutical Intermediate Needs?

As a dedicated manufacturer and supplier, we offer 2-Methyl-1-Butanol that meets the high standards of the pharmaceutical industry. We provide competitive pricing and flexible ordering options, allowing you to purchase the quantities you need. Our commitment to quality and timely delivery makes us an ideal partner for your pharmaceutical synthesis projects. We encourage you to request a quote and explore how we can support your material needs.