For research and development scientists in the pharmaceutical sector, identifying and utilizing high-performance excipients is critical for developing effective drug formulations. Disodium Fumarate (CAS 17013-01-3) emerges as a compound of significant interest due to its multifaceted roles. As a specialized supplier, we provide insights into why Disodium Fumarate is a valuable asset for pharmaceutical innovation.

Disodium Fumarate, a sodium salt of fumaric acid, is characterized by its white, odorless crystalline powder form. Its chemical structure, C4H2Na2O4, and a molecular weight of 160.04 g/mol, contribute to its predictable behavior in formulations. The compound's ability to maintain a pH range of 6-7 in a 33.3% aqueous solution makes it an excellent buffering agent.

Buffering and Stabilization Properties

One of the primary advantages of Disodium Fumarate in pharmaceutical applications is its efficacy as a buffering agent. Maintaining a stable pH is crucial for the stability of many active pharmaceutical ingredients (APIs), particularly those sensitive to pH fluctuations. By incorporating Disodium Fumarate, scientists can ensure that their formulations remain within the optimal pH range, thus preserving API integrity and extending product shelf life. This buffering capacity is vital for oral solid dosage forms, where maintaining a consistent micro-environmental pH can significantly influence drug solubility and absorption.

Role as a Disintegrant

Disodium Fumarate also exhibits properties that can aid in drug dissolution. As a disintegrant, it helps tablets and capsules to break apart rapidly upon contact with gastrointestinal fluids. This process is essential for releasing the API, allowing for effective absorption and subsequent therapeutic action. For R&D scientists focused on improving drug delivery and bioavailability, particularly for poorly soluble compounds, Disodium Fumarate can be a valuable component in formulation design.

Considerations for Sourcing

When sourcing Disodium Fumarate for pharmaceutical use, purity is paramount. Our commitment as a manufacturer is to provide a product with an assay of 98.0-102.0% and extremely low levels of impurities, such as heavy metals and sulfates. This ensures that the excipient meets the stringent requirements of the pharmaceutical industry. We encourage scientists to request our product specifications and samples to verify suitability for their specific research and development projects. Purchasing from a reliable supplier like us guarantees that you receive materials that meet the highest standards for pharmaceutical applications.

For any research scientist or formulator looking to buy Disodium Fumarate to enhance their drug formulations, we offer a reliable and high-quality source. Contact us to discuss your needs and obtain a quote.