For professionals engaged in the chemical, flavor, and pharmaceutical industries, a thorough understanding of key intermediates like 2-Pyrazinylethanethiol (CAS 35250-53-4) is crucial for successful operations. This compound, characterized by its distinctive sulfurous and meaty aroma, plays a significant role in flavor enhancement and serves as a vital building block in organic synthesis. Mastering its sourcing and handling best practices ensures both product quality and operational safety.

Key Properties and Applications:

2-Pyrazinylethanethiol is a liquid, typically appearing as white to yellow and transparent. Its chemical formula is C6H8N2S, with a molecular weight of 140.21. It boasts a notable boiling point of 105-110 °C at 20 mm Hg and a flash point above 230 °F. Its primary applications include:

  • Flavor and Fragrance Industry: Imparting savory, meaty, and sulfurous notes to foods and fragrances.
  • Organic Synthesis: Acting as a critical intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals due to its reactive thiol group and pyrazine ring.
  • Research and Development: Used by scientists exploring new flavor compounds and synthetic pathways.

Best Practices for Sourcing:

When purchasing 2-Pyrazinylethanethiol, prioritizing purity (commonly 98%min) and consistency is paramount. Buyers should seek out reputable manufacturers and suppliers, particularly those based in China, known for their robust production capabilities and competitive pricing. Always request a Certificate of Analysis (CoA) to verify product specifications and a Safety Data Sheet (SDS) for handling guidelines. For bulk purchases, direct engagement with manufacturers can secure better pricing and a more stable supply chain.

Safe Handling and Storage:

Due to its strong odor and potential irritant properties, proper handling of 2-Pyrazinylethanethiol is essential. It should be stored in a cool, dark place, preferably under an inert atmosphere to prevent oxidation of the thiol group. Ensure adequate ventilation when working with the chemical, and use appropriate personal protective equipment (PPE), including gloves, eye protection, and respiratory protection if necessary. Its storage instructions typically recommend room temperature or refrigerated conditions (2-8°C) to maintain stability. Familiarizing yourself with the hazard statements (e.g., H301 - Toxic if swallowed, H315 - Causes skin irritation) and precautionary statements provided in the SDS is critical for safe laboratory or industrial use.

By adhering to these sourcing and handling guidelines, businesses can effectively integrate 2-Pyrazinylethanethiol (CAS 35250-53-4) into their processes, ensuring both quality outcomes and a safe working environment. For your procurement needs, consider established chemical suppliers who offer reliable service and product integrity.