The Chemistry Behind 2,3-Difluorophenetole: Properties and Synthesis
Understanding the fundamental chemistry of specialized intermediates is key for researchers and formulators. 2,3-Difluorophenetole (CAS: 121219-07-6) is a fascinating molecule whose unique structure dictates its broad utility. As a leading manufacturer and supplier of fine chemicals, we are pleased to share insights into the properties and synthesis that make this compound so valuable.
The molecular formula for 2,3-Difluorophenetole is C8H8F2O, with a molecular weight of 158.15 g/mol. Its physical properties are characteristic of many aromatic ethers: it is typically a colorless to light yellow transparent liquid with a boiling point around 178°C and a density of approximately 1.1784. The presence of two fluorine atoms on the benzene ring at the ortho and meta positions relative to the ethoxy group significantly influences its electronic distribution and reactivity. This specific arrangement of substituents makes it an attractive precursor for targeted synthesis.
The synthesis of 2,3-Difluorophenetole typically involves etherification reactions starting from a suitable difluorophenol precursor. While specific industrial synthesis routes are proprietary, general approaches often involve nucleophilic substitution reactions or Ullmann-type condensations. The careful control of reaction conditions is paramount to achieve the high purity (≥99.0% assay) required for its demanding applications, particularly in liquid crystal and pharmaceutical intermediate manufacturing. We ensure robust synthesis protocols to deliver consistent quality when you buy this compound.
The chemical properties stemming from the difluorinated phenyl ether structure are what make 2,3-Difluorophenetole so sought after. The fluorine atoms impart electron-withdrawing effects, influencing the reactivity of the aromatic ring and any attached functional groups. This can also lead to enhanced thermal stability and altered solubility profiles compared to non-fluorinated analogs. As a reliable supplier, we emphasize these characteristics when discussing its application in sophisticated organic synthesis.
For those looking to source this critical intermediate, understanding its chemical profile is the first step. We invite chemists and procurement specialists to explore our offerings and request a quote for 2,3-Difluorophenetole. Whether for R&D or large-scale production, our commitment as a China-based manufacturer is to provide high-quality chemical solutions. Partner with us to leverage the unique chemistry of 2,3-Difluorophenetole in your next project.
Perspectives & Insights
Molecule Vision 7
“As a reliable supplier, we emphasize these characteristics when discussing its application in sophisticated organic synthesis.”
Alpha Origin 24
“For those looking to source this critical intermediate, understanding its chemical profile is the first step.”
Future Analyst X
“We invite chemists and procurement specialists to explore our offerings and request a quote for 2,3-Difluorophenetole.”