In the realm of scientific research and laboratory diagnostics, the reliability and performance of reagents are paramount. Among the most fundamental tools available to researchers are detergents, which play a crucial role in cell biology, biochemistry, and molecular biology. Octylphenylpolyethylene Glycol (CAS 9002-93-1), a widely recognized nonionic detergent, is an indispensable component in many laboratory protocols. As a trusted chemical supplier, we provide high-quality Octylphenylpolyethylene Glycol to support your critical research endeavors.

Octylphenylpolyethylene Glycol: A Laboratory Staple

Octylphenylpolyethylene Glycol, often known by its CAS number 9002-93-1 or various trade names, is a nonionic surfactant renowned for its mild yet effective detergent properties. Its unique molecular structure allows it to disrupt lipid bilayers and solubilize membrane proteins without causing significant denaturation, making it a preferred choice for many sensitive biological applications.

Key Laboratory Applications:

The versatility of Octylphenylpolyethylene Glycol makes it a staple in many laboratory workflows:

  • Cell Lysis: It is extensively used to lyse cell membranes, releasing intracellular components such as proteins, nucleic acids, and organelles for further analysis. This process is fundamental for protein extraction and studying cellular pathways.
  • Protein Solubilization: For membrane-bound proteins that are often difficult to isolate and study, Octylphenylpolyethylene Glycol effectively solubilizes them, allowing for biochemical characterization while largely preserving their native conformation.
  • Immunohistochemistry (IHC) and Immunofluorescence (IF): In these techniques, it is used to permeabilize cell membranes, allowing antibodies to access intracellular targets. It also helps reduce non-specific binding.
  • Enzyme Assays: It can be included in buffers for enzyme assays to ensure that enzymes remain soluble and active.
  • Disruption of Cell Monolayers: In various studies, it's used to disrupt cell monolayers as a positive control for measurements like Transepithelial Electrical Resistance (TEER).

Procuring High-Quality Reagents for Research

For laboratory managers and researchers, sourcing Octylphenylpolyethylene Glycol requires attention to quality and reliability. While it's a common chemical, the performance can vary based on purity and manufacturing standards. When purchasing for research, consider:

  • Purity and Grade: Look for reagents specified for laboratory or molecular biology use, ensuring they are free from inhibitory contaminants like nucleases. A high assay (e.g., 99%) is typically desired.
  • Supplier Reputation: Choose suppliers known for consistent quality and reliable delivery. Companies that provide detailed Certificates of Analysis (CoA) for each lot offer transparency and assurance.
  • Specific Applications: For some highly sensitive assays, specialized grades (e.g., low UV absorbance or nuclease-free) might be necessary.
  • Value for Money: While quality is paramount, comparing prices from reputable suppliers can help optimize laboratory budgets. Buying in larger quantities or from direct manufacturers can offer cost savings.

We understand the critical role that reliable reagents play in scientific discovery. Our Octylphenylpolyethylene Glycol is manufactured to high standards, ensuring its suitability for a wide range of laboratory applications. We invite researchers and procurement specialists to buy from us, confident in our commitment to quality and service. Contact us for a quote and to learn more about how we can support your laboratory's needs.