For chemists and material scientists, a deep understanding of a chemical intermediate's properties is fundamental to its effective application. 5-Bromo-1-benzofuran-2-carbaldehyde (CAS 23145-16-6) is an organic compound that offers a unique combination of chemical reactivity and structural characteristics, making it a valuable asset in various synthetic endeavors. This article aims to provide a comprehensive overview of its properties and discuss its broad applications.

Physically, 5-Bromo-1-benzofuran-2-carbaldehyde is typically described as a white to light yellow crystalline powder. Its molecular formula is C9H5BrO2, with a molecular weight of approximately 225.04 g/mol. Key physical properties reported include a melting point of around 129°C and a boiling point of approximately 312.4°C at atmospheric pressure. These characteristics indicate its stability under standard laboratory conditions and suggest appropriate handling and storage procedures. When considering purchasing this chemical, it's important to note that purity levels often reach 99%, a critical factor for precision in advanced synthesis.

Chemically, the molecule features a benzofuran ring system substituted with a bromine atom at the 5-position and an aldehyde group at the 2-position. The aldehyde group is highly reactive and can participate in numerous organic reactions, such as Wittig reactions, Grignard additions, and reductive aminations. The bromine atom provides a handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig), enabling the introduction of various functional groups and the construction of more complex molecular architectures. This dual reactivity makes it a sought-after intermediate for building diverse organic frameworks.

The applications of 5-Bromo-1-benzofuran-2-carbaldehyde span several advanced fields. In the electronics industry, it serves as a precursor for synthesizing organic semiconductors used in OLEDs, contributing to the development of efficient and vibrant display technologies. In the pharmaceutical sector, it acts as a key building block for APIs, facilitating the creation of drug candidates with potential therapeutic benefits. Researchers also utilize it in general organic synthesis to create novel molecules with specific properties for materials science and chemical research. For those looking to buy this compound, collaborating with established manufacturers and suppliers, especially those in China known for their competitive pricing and quality, is highly recommended for securing reliable quantities for your projects.