N2-[(phenylmethoxy)carbonyl]-L-lysine, commonly abbreviated as Z-Lys-OH or N-alpha-Cbz-L-lysine, with CAS number 2212-75-1, is a protected amino acid derivative that serves as a critical intermediate in various chemical synthesis pathways. Its dual functionality – the amine group protected by a stable benzyloxycarbonyl (Cbz) group and the reactive side-chain amine of lysine – makes it a versatile building block for organic chemists and material scientists.

The synthesis of N2-[(phenylmethoxy)carbonyl]-L-lysine typically involves the protection of the alpha-amino group of L-lysine. This is often achieved by reacting L-lysine with benzyl chloroformate (Cbz-Cl) under controlled alkaline conditions. The selection of appropriate reaction parameters, such as pH, temperature, and solvent, is crucial to ensure regioselectivity and high yield, while minimizing side reactions and racemization. Manufacturers specializing in amino acid derivatives invest heavily in optimizing these synthesis processes to achieve the high purity (often 99%) demanded by their clients.

The applications of N2-[(phenylmethoxy)carbonyl]-L-lysine are diverse, spanning several key industrial sectors. In the pharmaceutical industry, it is a vital intermediate for the synthesis of peptides and other complex drug molecules. Its presence allows for controlled chain elongation in peptide synthesis, ensuring the correct sequence and structure of biologically active peptides. Researchers in academia and industry frequently buy Z-Lys-OH for its utility in developing novel therapeutic agents.

Beyond pharmaceuticals, this compound finds applications in material science, particularly in the development of specialty polymers and electronic materials. Its incorporation into polymer backbones can impart unique properties, such as enhanced biocompatibility or specific optical characteristics, making it relevant for fields like OLED technology. The consistent availability of high-purity Z-Lys-OH from reliable suppliers, including many leading manufacturers in China, is essential for driving innovation in these advanced fields.

For any organization looking to source CAS 2212-75-1, understanding its synthetic routes and application scope empowers informed purchasing decisions. Partnering with experienced chemical manufacturers ensures not only the quality of the intermediate but also provides access to technical expertise and reliable supply chains, facilitating seamless integration into your research and production processes.