Understanding the Chemistry: Synthesis and Properties of 3-Bromo-9-phenylcarbazole
For chemists and material scientists, understanding the fundamental chemistry behind key intermediates is crucial for successful application and development. 3-Bromo-9-phenylcarbazole (CAS 1153-85-1) is one such compound, a vital building block in the synthesis of advanced materials for OLEDs and in the production of pharmaceutical compounds. This article explores its synthesis pathways and characteristic properties, offering insights valuable to those looking to buy or utilize this chemical.
The synthesis of 3-Bromo-9-phenylcarbazole typically involves N-phenylation of 3-bromo-9H-carbazole. Common methods employ palladium catalysis, such as the Buchwald-Hartwig amination or Ullmann-type coupling reactions, using reagents like iodobenzene or bromobenzene in the presence of suitable ligands and bases. These reactions are carefully controlled to ensure high yields and purity, minimizing side products that could affect downstream applications. The resulting compound, a white to off-white powder, boasts a molecular formula of C18H12BrN and a molecular weight of approximately 322.20 g/mol.
Key properties that make 3-Bromo-9-phenylcarbazole valuable include its thermal stability, measured by a relatively high boiling point, and its specific electronic characteristics derived from the carbazole core and the phenyl substituent. The bromine atom serves as a reactive handle for further functionalization, enabling chemists to build more complex molecular structures through various cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira couplings). This versatility is precisely why it is a sought-after intermediate for researchers and manufacturers aiming to buy materials for cutting-edge applications.
The compound's solubility profile, typically showing slight solubility in water but better solubility in organic solvents like dichloromethane or toluene, is also important for its processing and reaction conditions. Understanding these chemical nuances is essential for anyone involved in purchasing or using this intermediate. For industrial applications, particularly in OLED manufacturing, purity levels often need to be extremely high, necessitating advanced purification techniques by the supplier.
As a leading chemical supplier, we are dedicated to providing 3-Bromo-9-phenylcarbazole that meets these exacting standards. Our manufacturing processes are designed to yield a product with consistent quality, making it an ideal choice for demanding synthetic procedures in both research laboratories and industrial production environments. By offering this well-characterized intermediate, we support innovation in electronic materials and pharmaceuticals.
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Data Seeker X
“Understanding these chemical nuances is essential for anyone involved in purchasing or using this intermediate.”
Chem Reader AI
“For industrial applications, particularly in OLED manufacturing, purity levels often need to be extremely high, necessitating advanced purification techniques by the supplier.”
Agile Vision 2025
“As a leading chemical supplier, we are dedicated to providing 3-Bromo-9-phenylcarbazole that meets these exacting standards.”