For any chemical intermediate, understanding its synthesis and safety protocols is as crucial as knowing its applications. 2-Bromofluorene (CAS 1133-80-8) is a widely used compound in organic synthesis, particularly for OLED materials and pharmaceutical intermediates. As a leading manufacturer of 2-Bromofluorene in China, NINGBO INNO PHARMCHEM CO.,LTD. prioritizes both quality in synthesis and safety in handling.

The synthesis of 2-Bromofluorene typically involves the electrophilic aromatic substitution of fluorene. A common laboratory and industrial method uses N-bromosuccinimide (NBS) as the brominating agent, often in a solvent like propylene carbonate or acetic acid. The reaction conditions, including temperature, reaction time, and the molar ratio of reactants, are carefully controlled to optimize the yield and purity of 2-Bromofluorene and minimize the formation of byproducts like 2,7-dibromofluorene. Following synthesis, purification steps such as recrystallization are employed to achieve the high purity levels required for its applications.

When considering the safety of 2-Bromofluorene, it is important to note that while it is generally handled with standard laboratory precautions, it is classified as an irritant. As per safety data sheets, direct contact with skin, eyes, and inhalation of dust or vapors should be avoided. Adequate personal protective equipment (PPE), including gloves, safety glasses, and lab coats, is essential when working with this compound. Proper ventilation in the workspace is also critical.

For industrial users, understanding storage conditions is also vital. 2-Bromofluorene should be stored in a cool, dry, and well-ventilated area, away from incompatible materials and sources of ignition. As a fine chemical supplier, NINGBO INNO PHARMCHEM CO.,LTD. provides detailed safety information and handles packaging and transportation with care to ensure product integrity and safety.

For businesses looking to secure a reliable supply of 2-Bromofluorene, sourcing from a trusted supplier of 2-Bromofluorene in China is advantageous. We offer competitive prices for 2-Bromofluorene and ensure that our products meet stringent quality standards. Whether you are using it as an organic synthesis building block or for specialized material production, NINGBO INNO PHARMCHEM CO.,LTD. is your dependable partner for high-quality 2-Bromofluorene.