Carbamoyloxyurea, identified by its CAS number 4543-62-8, is a chemical compound that has garnered increasing attention in the scientific community for its unique properties and potential applications. As a key intermediate and research chemical, understanding its synthesis, physical characteristics, and diverse research avenues is crucial for scientists and procurement professionals alike. This article delves into these aspects, offering valuable insights for those looking to purchase or utilize this compound.

Synthesis and Preparation Methods

The synthesis of Carbamoyloxyurea can be approached through various methods. One notable pathway involves the controlled oxidation of hydroxyurea. Optimization of reaction conditions, such as temperature, pH, and reaction duration, is paramount to achieving high yields and purity. For instance, studies indicate that incubating hydroxyurea solutions at moderate temperatures (e.g., 37°C) under neutral pH conditions can yield this compound. However, elevated temperatures can accelerate decomposition and lead to undesired byproducts. Advanced synthesis may involve specific chemical oxidation systems designed for higher purity, often yielding products above 95%. Researchers aiming to buy Carbamoyloxyurea should inquire about the specific synthesis route and purity levels offered by the manufacturer.

Physicochemical Properties and Stability

Carbamoyloxyurea typically presents as a white powder. Its molecular formula is C₂H₅N₃O₃, with a molecular weight of approximately 119.08 g/mol. The compound exhibits a melting point in the range of 158-160°C, indicating moderate thermal stability. Its solubility in water is attributed to the presence of polar functional groups. For optimal storage, it is recommended to keep Carbamoyloxyurea in a tightly closed container in a dry, well-ventilated, and cool place. Understanding these properties is essential for effective handling and storage, ensuring the compound's integrity from purchase through to its application in research.

Scientific Research Applications

The scientific interest in Carbamoyloxyurea stems from its demonstrated biological activities and chemical versatility. In cancer research, it is being investigated for its ability to inhibit cell division by targeting ribonucleotide reductase, a crucial enzyme in DNA synthesis. This mechanism suggests potential as a therapeutic agent to hinder cancer cell proliferation. Furthermore, its antimicrobial studies have shown significant bactericidal properties, particularly against strains like Escherichia coli. The compound's lethal action appears to be independent of cellular metabolism, distinguishing it from other agents and offering a unique angle for developing new antimicrobial solutions. Researchers seeking to buy this compound for such studies can find reliable suppliers offering high-quality grades.

Procurement and Quality Assurance

When sourcing Carbamoyloxyurea, it is vital to partner with a reputable manufacturer or supplier. Companies specializing in research chemicals and fine chemical intermediates, especially those based in China, often provide competitive pricing and efficient delivery. Ensuring the purity and quality of Carbamoyloxyurea is paramount for reproducible research outcomes. Always verify the assay percentage, any accompanying analytical data (like NMR or HPLC), and storage recommendations. For bulk purchases or to get the latest factory price, contacting a trusted supplier directly is the best approach.

In conclusion, Carbamoyloxyurea (CAS 4543-62-8) is a compound with significant promise in both chemical research and potential therapeutic applications. Its accessible synthesis, distinct properties, and ongoing investigation in critical scientific fields make it a valuable chemical for researchers and industry professionals.