In the intricate world of organic chemistry, understanding the fundamental properties and synthesis routes of key intermediates is crucial for chemists and formulators. NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing access to high-purity organic compounds, including 1,3-Bis(4,5-dihydro-2-oxazolyl)benzene (CAS: 34052-90-9). This compound, a vital building block in polymer science, possesses unique chemical characteristics that dictate its utility. For scientists and procurement specialists looking to buy this chemical, knowledge of its synthesis and reactivity is paramount.

1,3-Bis(4,5-dihydro-2-oxazolyl)benzene is characterized by its molecular formula C12H12N2O2 and a molecular weight of approximately 216.24 g/mol. Structurally, it features a central benzene ring substituted at the 1 and 3 positions with 4,5-dihydro-2-oxazolyl groups. These five-membered heterocyclic rings, containing a carbon-nitrogen double bond, impart significant reactivity. The compound's melting point typically falls within the range of 147-151°C, and it appears as a white to light-colored powder or crystal. Its relative insolubility in water but solubility in common organic solvents is also a key property for processing.

The chemical properties of 1,3-Bis(4,5-dihydro-2-oxazolyl)benzene are largely defined by the oxazoline rings. These rings are known to undergo facile ring-opening reactions with nucleophiles, particularly at elevated temperatures. This reactivity makes it an excellent candidate for reactions with carboxylic acids, acid anhydrides, amines, epoxides, and thiols. In polymer applications, this means it can effectively react with terminal functional groups of polymer chains, enabling chain extension or cross-linking reactions. This capability is precisely what makes it invaluable for improving polymer properties such as melt strength, thermal stability, and hydrolytic resistance.

The synthesis of 1,3-Bis(4,5-dihydro-2-oxazolyl)benzene typically involves the reaction of isophthalonitrile with 2-aminoethanol in the presence of a catalyst, often a cobalt compound and sulfur, at elevated temperatures or under microwave irradiation. While specific synthesis protocols can vary, the core principle involves the cyclization and condensation to form the oxazoline rings. Ensuring high purity requires careful control of reaction conditions and subsequent purification steps, such as column chromatography.

For researchers and industries looking to buy this versatile intermediate, sourcing from a reputable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. is essential. We are committed to providing 1,3-PBO that meets stringent purity standards, crucial for predictable and effective chemical synthesis and polymer modification. Our expertise ensures you receive a product that aligns with your technical requirements. Contact us to learn more about the chemical properties and synthesis of 1,3-Bis(4,5-dihydro-2-oxazolyl)benzene and to arrange your purchase.