The field of organic chemistry is constantly evolving, with a continuous search for versatile building blocks that can unlock new synthetic pathways and material properties. 1,2-Difluoroethane (CAS 624-72-6) has emerged as a compound of significant interest, offering unique fluorination capabilities that are highly valued across various industrial sectors. This article serves as a guide for chemists, researchers, and procurement professionals seeking to understand and source this important chemical intermediate.

Understanding 1,2-Difluoroethane: Properties and Characteristics

1,2-Difluoroethane, identified by CAS number 624-72-6, is a colorless gas with a molecular formula of C2H4F2. Its key physical properties include a boiling point of 31°C, a density of 0.913 g/cm³, and a refractive index of 1.254. It is commonly supplied with a minimum purity of 95%. The presence of two fluorine atoms attached to adjacent carbon atoms makes it a potent precursor for introducing specific fluorinated functional groups into more complex molecules. This strategic fluorination can impart desirable characteristics such as increased thermal stability, enhanced chemical resistance, altered electronic properties, and modified biological activity.

Industrial Applications: A Versatile Intermediate

The industrial utility of 1,2-Difluoroethane is broad, primarily stemming from its role as a chemical intermediate. Its applications include:

  • Pharmaceutical Synthesis: In the development of new drugs, fluorine incorporation is a common strategy to improve pharmacokinetic properties like absorption, distribution, metabolism, and excretion (ADME). Researchers often aim to buy 1,2-difluoroethane as a starting material to synthesize fluorinated pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
  • Agrochemical Development: Similar to pharmaceuticals, fluorine substitution in agrochemicals can lead to more potent and environmentally stable pesticides, herbicides, and fungicides. 1,2-Difluoroethane is a valuable reagent for creating these advanced crop protection agents.
  • Specialty Chemical Production: Beyond life sciences, it finds applications in the synthesis of specialty chemicals for electronics, advanced materials, and performance polymers where fluorination is required to achieve specific properties.
  • Research and Exploration: For academic and industrial research, 1,2-Difluoroethane is instrumental in exploring novel fluorination reactions and developing new fluorinated compounds with potentially groundbreaking applications.

Procuring 1,2-Difluoroethane: Tips for Buyers

For companies looking to secure a reliable supply of 1,2-Difluoroethane, understanding the market and procurement best practices is essential. China is a significant global producer of specialty chemicals, offering competitive pricing and diverse sourcing options. When considering a purchase, buyers should focus on:

  • Purity Levels: Ensure the supplier can consistently provide the specified purity (e.g., 95% min) to meet your application's demands.
  • Supplier Reputation: Research potential manufacturers and suppliers for their track record, quality control processes, and customer service.
  • Competitive Pricing: Inquiring about the 1,2-difluoroethane price from multiple sources, particularly within China, can help secure cost advantages.
  • Technical Data and Support: Working with a supplier that offers comprehensive technical documentation and support can facilitate smooth integration into your processes.

Companies such as NINGBO INNO PHARMCHEM CO.,LTD. are known for their commitment to quality and reliability in supplying specialized chemical intermediates like 1,2-Difluoroethane. Engaging with such established entities ensures that your procurement needs are met efficiently and effectively.

In summary, 1,2-Difluoroethane is a critical fluorinated intermediate with far-reaching applications in chemical manufacturing. By understanding its properties and adopting a strategic approach to procurement, businesses can leverage this compound to drive innovation and product development.