For professionals in the chemical synthesis sector, a thorough understanding of key reagents and intermediates is fundamental. 1,4-Dichlorobutane, identified by CAS number 110-56-5, is a compound that merits close attention due to its diverse applications in organic synthesis, particularly as a pharmaceutical intermediate and a versatile chemical solvent. This article delves into the properties of 1,4-Dichlorobutane and highlights its significance for researchers and manufacturers seeking to purchase high-quality chemical compounds.

Chemical Profile of 1,4-Dichlorobutane
1,4-Dichlorobutane is a chlorinated alkane with the chemical formula C4H8Cl2. It presents as a clear, colorless liquid with a characteristic odor. Its physical properties, such as a melting point of -38 °C and a boiling point ranging from 161-163 °C, indicate its state at standard laboratory conditions. The density is approximately 1.16 g/mL at 25 °C. These properties are vital for chemists to consider when designing reaction parameters or selecting appropriate solvents. The compound's molecular structure, with chlorine atoms at opposite ends of a four-carbon chain, contributes to its reactivity and utility in various chemical transformations.

Key Role in Organic Synthesis and Pharmaceutical Development
The primary utility of 1,4-Dichlorobutane lies in its role as an intermediate in organic synthesis. It is a precursor in the production of adiponitrile, a critical component in the manufacturing of nylon. Furthermore, its designation as an active pharmaceutical intermediate means it is a sought-after compound for the synthesis of various medicinal drugs. For research scientists and procurement managers, understanding these applications is key to identifying potential suppliers and ensuring they purchase a product that meets specific purity and performance requirements. Sourcing from reliable manufacturers is essential for consistent results.

Selecting a Reputable Manufacturer and Supplier
When seeking to buy 1,4-Dichlorobutane, partnering with a reputable manufacturer is crucial. Companies like NINGBO INNO PHARMCHEM CO.,LTD., a prominent supplier in China, offer this chemical with guaranteed quality and competitive pricing. Procurement specialists should always request detailed product specifications and Certificates of Analysis (CoAs) to confirm purity and suitability for their intended use. The ability of a supplier to provide consistent batch quality and manage logistics effectively is paramount for R&D and production continuity. Inquiring about pricing and bulk order discounts from established manufacturers can also lead to significant cost savings.

Technical Specifications and Handling Considerations
Key technical specifications for 1,4-Dichlorobutane include its purity (often specified as 97% or higher by GC), refractive index, and solubility. While it is soluble in water to some extent, it is generally more soluble in organic solvents. For safe handling, it is important to adhere to standard laboratory safety protocols, including the use of personal protective equipment (PPE) and working in well-ventilated areas, as indicated by its Safety Data Sheet (SDS). Proper storage, typically below +30°C and in a dry, cool place, is also recommended to maintain product integrity.

In conclusion, 1,4-Dichlorobutane (CAS 110-56-5) is a cornerstone chemical for many synthetic processes. By understanding its properties and applications, and by engaging with reliable chemical manufacturers and suppliers, the procurement process can be streamlined, ensuring access to this vital compound for your chemical needs.