The pharmaceutical industry relies heavily on the precise synthesis of complex organic molecules. Within this domain, certain chemical intermediates play a pivotal role, acting as foundational building blocks for active pharmaceutical ingredients (APIs). 1-Bromo-3,4-dichlorobenzene (CAS 18282-59-2) is one such critical compound, valued for its structural characteristics and reactivity in crafting advanced pharmaceutical intermediates.

Understanding 1-Bromo-3,4-dichlorobenzene's Significance

1-Bromo-3,4-dichlorobenzene is a halogenated aromatic hydrocarbon with the molecular formula C6H3BrCl2. Its structure, featuring a bromine atom and two chlorine atoms affixed to a benzene ring, makes it a versatile starting material in synthetic organic chemistry. Typically available with a purity of 98% or higher, it is usually encountered as a clear to slightly yellow liquid. Its melting point is close to ambient temperature (23-24°C), which can affect its physical state. For researchers and procurement specialists looking to buy 1-Bromo-3,4-dichlorobenzene, understanding these properties is key to its effective application.

Applications in Pharmaceutical Synthesis

The primary contribution of 1-Bromo-3,4-dichlorobenzene to the pharmaceutical sector lies in its role as a key intermediate. It is instrumental in the synthesis of various complex organic molecules that form the basis of new drug candidates. The strategically placed halogen atoms allow for regioselective reactions, enabling chemists to precisely build molecular structures. For instance, it is utilized in the synthesis of N-arylated sultams, which have shown promise in drug discovery efforts. Furthermore, its bromine atom serves as an excellent leaving group for cross-coupling reactions, facilitating the formation of C-C and C-N bonds, which are fundamental in constructing API scaffolds.

As a leading aryl halide manufacturer, we recognize the stringent demands of the pharmaceutical industry. Our production of 1-Bromo-3,4-dichlorobenzene (CAS 18282-59-2) adheres to high purity standards, ensuring that it meets the exacting requirements for pharmaceutical intermediate synthesis. Partnering with a reliable chemical synthesis intermediate supplier is crucial for maintaining the integrity and efficacy of the final pharmaceutical product.

Procurement and Quality Assurance for Pharmaceutical Needs

When sourcing for pharmaceutical R&D or manufacturing, meticulous attention to quality and supplier reliability is paramount. It is essential to work with a reputable supplier in China or elsewhere that can provide comprehensive documentation, including Certificates of Analysis (CoA) and Safety Data Sheets (SDS), to confirm product purity and safe handling procedures. Understanding the competitive price of 1-Bromo-3,4-dichlorobenzene is important, but it should always be balanced against the supplier’s commitment to quality and regulatory compliance. Investing in a high-quality intermediate from a trusted source ensures a more predictable and successful synthesis process.

The availability of high-purity 1-Bromo-3,4-dichlorobenzene from trusted manufacturers empowers pharmaceutical researchers to develop innovative treatments. Its role as a versatile intermediate underscores its importance in the ongoing advancement of medicinal chemistry.