For professionals in organic chemistry, understanding the specific properties and application potential of a chemical compound is the first step towards successful synthesis and innovation. 1-Bromo-3-fluoro-5-iodobenzene, bearing the CAS number 845866-85-5, is a prime example of a versatile and highly sought-after organic building block. This tri-halogenated benzene derivative is prized for its unique reactivity, making it an indispensable component in the creation of complex molecular architectures. Researchers and chemists often look to buy this compound from specialized chemical suppliers to ensure the quality and consistency required for advanced synthetic procedures.

Understanding the Chemical Profile

The molecular formula of 1-Bromo-3-fluoro-5-iodobenzene is C6H3BrFI, with a molecular weight of approximately 300.90 g/mol. These fundamental properties are crucial for stoichiometric calculations in reactions. Further physical characteristics, such as a boiling point of 242°C at 760 mmHg and a flash point of 100.1°C, provide important safety and handling information for laboratory and industrial settings. Its appearance is typically described as a liquid, making it relatively easy to handle and dispense in various reaction setups. The typical purity offered by reliable manufacturers is often 95% or higher, ensuring that the compound is suitable for demanding applications where impurities could interfere with desired chemical transformations.

Applications Driving Demand

The strategic placement of three different halogens on the benzene ring grants 1-Bromo-3-fluoro-5-iodobenzene exceptional versatility in organic synthesis. It serves as a foundational intermediate for a multitude of chemical reactions, particularly those involving transition-metal catalyzed cross-couplings. Scientists frequently use it to introduce specific functional groups or to build complex carbon frameworks in the synthesis of:

  • Pharmaceutical Ingredients: As a key intermediate in the synthesis of novel drug candidates, its structure can be elaborated to form active pharmaceutical ingredients (APIs) with targeted therapeutic properties.
  • Agrochemicals: Similar to pharmaceuticals, this compound can be incorporated into the synthesis pathways for new pesticides, herbicides, or fungicides, aiming for enhanced efficacy and selectivity.
  • Materials Science: The compound's unique electronic and structural properties make it a valuable precursor for developing advanced materials, including organic light-emitting diodes (OLEDs), liquid crystals, and specialty polymers.
  • Research & Development: In academic and industrial research labs, it serves as a go-to reagent for exploring new synthetic methodologies and constructing intricate molecular targets.

Sourcing and Quality Assurance

When you need to buy 1-Bromo-3-fluoro-5-iodobenzene, it is essential to partner with reputable chemical suppliers or manufacturers who can guarantee the stated purity and provide comprehensive documentation. A reliable manufacturer will offer detailed product specifications, including CAS number, molecular formula, and physical properties, along with a Certificate of Analysis (CoA) for each batch. This diligence ensures that your procurement aligns with the high standards required for sensitive research and development projects. By choosing a trusted supplier, you ensure the efficiency and success of your synthetic endeavors, whether you are looking for small research quantities or bulk industrial supply.