In the precise world of analytical chemistry, the selection and sourcing of internal standards are paramount for ensuring the accuracy and reliability of experimental results. 1-Chlorooctadecane (CAS 3386-33-2) has carved out a significant niche as an internal standard, particularly in environmental analysis. For laboratories and research institutions requiring this compound, understanding its analytical applications and sourcing it from trusted manufacturers is key.

The Function of 1-Chlorooctadecane in Analytical Chemistry

1-Chlorooctadecane is widely utilized as an internal standard in various chromatographic techniques, most notably in conjunction with stir bar sorptive extraction (SBSE). SBSE is a powerful sample preparation technique used for concentrating trace organic contaminants from aqueous samples before analysis by gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-mass spectrometry (LC-MS).

The role of an internal standard is to compensate for variations in sample preparation, injection volumes, and detector response that can occur during the analytical process. 1-Chlorooctadecane is chosen for this purpose due to its:

  • Chemical Similarity: Its long aliphatic chain and single chlorine atom make it chemically similar to many target analytes, ensuring it behaves comparably during extraction and chromatography.
  • Distinct Mass/Retention Time: It has a unique mass spectrum and chromatographic retention time, allowing it to be easily distinguished from the analytes of interest.
  • Availability in High Purity: Crucially, 1-Chlorooctadecane can be synthesized and purified to very high standards, essential for an internal standard which must be of known and consistent composition.
  • Low Background Interference: Its presence in environmental samples at significant levels is unlikely, minimizing potential background interference.

Specific applications include the determination of endocrine-disrupting compounds (EDCs) in water samples, such as pharmaceuticals, personal care products, and pesticides. By adding a known amount of 1-Chlorooctadecane to samples before extraction, analysts can accurately quantify the target analytes even if there are minor losses or variations in the procedure.

Sourcing High-Purity 1-Chlorooctadecane for Analytical Use

For analytical applications, the purity and traceability of 1-Chlorooctadecane are non-negotiable. When looking to 'buy 1-chlorooctadecane' for your laboratory, prioritize suppliers who:

  • Offer Certified Reference Materials: Some suppliers provide 1-Chlorooctadecane specifically certified for analytical use, often with detailed documentation on purity and uncertainty.
  • Provide Comprehensive Certificates of Analysis (CoA): Ensure the CoA includes high-precision purity data (e.g., >99.5% or higher) and confirmation of identity via techniques like GC-MS or NMR.
  • Have Robust Quality Control: Reputable manufacturers will have stringent quality control measures in place throughout their production process.
  • Offer Consistent Lot-to-Lot Quality: For ongoing analytical work, maintaining consistency between different batches of the internal standard is vital for reproducible results.

When you search for '1-chlorooctadecane supplier China,' look for companies that explicitly state their suitability for analytical or research purposes. As a manufacturer dedicated to quality, we provide 1-Chlorooctadecane that meets the demanding specifications required for accurate environmental analysis and other critical laboratory applications. Contact us to discuss your specific purity requirements and to obtain a quotation.