1-Phenylethanol: A Key Chiral Building Block for Pharma
The pharmaceutical industry's relentless pursuit of targeted therapies and enantiomerically pure drugs places immense value on versatile chiral building blocks. Among these, 1-Phenylethanol stands out as a critical intermediate, offering a unique stereogenic center that is leveraged in the synthesis of a wide array of pharmacologically active compounds. For R&D scientists and procurement specialists, understanding how to buy 1-Phenylethanol with high enantiomeric excess (ee) from a trusted manufacturer is key to successful drug development.
The Significance of Chirality in Pharmaceuticals
Chirality, the property of a molecule being non-superimposable on its mirror image, is fundamental in pharmacology. Different enantiomers of a drug can exhibit vastly different biological activities, with one enantiomer often being therapeutic while the other may be inactive or even toxic. This necessitates the development of synthetic routes that produce enantiomerically pure or enriched compounds. 1-Phenylethanol, with its readily accessible chiral center, serves as an excellent starting material or intermediate in many such asymmetric syntheses.
1-Phenylethanol in Drug Synthesis
As a pharmaceutical intermediate, 1-Phenylethanol (CAS 98-85-1) is employed in the synthesis of various therapeutic agents. Its hydroxyl group and benzylic position offer multiple avenues for chemical modification. For instance, it can be esterified, oxidized, or undergo nucleophilic substitution reactions to introduce diverse functionalities. Procurement managers seeking to source 1-Phenylethanol for their synthesis pipelines should focus on suppliers who can guarantee specific enantiomeric forms, such as (S)-(-)-1-Phenylethanol or (R)-(+)-1-Phenylethanol, with high optical purity.
Finding Reliable Suppliers for Pharmaceutical Grade 1-Phenylethanol
When sourcing for pharmaceutical applications, it is crucial to partner with manufacturers who adhere to strict quality control measures. A reliable supplier will provide comprehensive documentation, including detailed Certificates of Analysis that confirm purity, enantiomeric excess, and impurity profiles. Understanding the pricing structure for such specialized grades is also essential for budgeting R&D and production costs. If you are looking to buy 1-Phenylethanol for your pharmaceutical needs, prioritize suppliers with a proven track record in producing intermediates for regulated industries.
As a leading manufacturer and supplier of fine chemical intermediates, we specialize in providing high-purity chiral compounds like 1-Phenylethanol. Our state-of-the-art facilities and rigorous quality assurance protocols ensure that our products meet the demanding standards of the pharmaceutical industry. We are dedicated to offering competitive 1-Phenylethanol prices and a stable supply chain, empowering our clients to advance their research and development with confidence. Contact us to discuss your specific requirements for chiral 1-Phenylethanol and to receive a detailed quote from a trusted supplier.
Perspectives & Insights
Bio Analyst 88
“Among these, 1-Phenylethanol stands out as a critical intermediate, offering a unique stereogenic center that is leveraged in the synthesis of a wide array of pharmacologically active compounds.”
Nano Seeker Pro
“For R&D scientists and procurement specialists, understanding how to buy 1-Phenylethanol with high enantiomeric excess (ee) from a trusted manufacturer is key to successful drug development.”
Data Reader 7
“The Significance of Chirality in PharmaceuticalsChirality, the property of a molecule being non-superimposable on its mirror image, is fundamental in pharmacology.”