2,4-Dimethylbenzenethiol: A Key Intermediate for Organic Synthesis
For R&D scientists and product formulation specialists in the chemical and pharmaceutical industries, identifying reliable sources for key chemical intermediates is a constant pursuit. 2,4-Dimethylbenzenethiol (CAS 13616-82-5) stands out as a valuable building block in organic synthesis. Its unique chemical structure and reactivity make it a sought-after compound for creating more complex molecules. This article explores its significance and guides B2B buyers on how to source it effectively.
Understanding the Chemistry of 2,4-Dimethylbenzenethiol
2,4-Dimethylbenzenethiol is a derivative of thiophenol, featuring two methyl groups attached to the benzene ring at the 2 and 4 positions. The presence of the thiol (-SH) group imparts significant reactivity. This functional group can participate in a wide array of chemical reactions, including nucleophilic substitutions, additions, and oxidations. Its properties, such as a melting point estimated at -30°C, a boiling point of 207-208 °C, and a density of 1.022 g/mL, are critical for handling and reaction design. As a clear to light yellow liquid, it possesses a characteristic stench and is flammable, necessitating adherence to safety protocols.
Versatility in Organic Synthesis Applications
The primary utility of 2,4-Dimethylbenzenethiol lies in its role as a chemical intermediate. It serves as a precursor in the synthesis of:
- Pharmaceuticals: The thiol group can be functionalized or used to introduce sulfur-containing moieties into drug candidates, potentially influencing their pharmacokinetic or pharmacodynamic properties.
- Agrochemicals: It can be a building block for creating pesticides, herbicides, or fungicides, contributing specific structural elements that impart biological activity.
- Specialty Chemicals: Its structure allows for the creation of diverse specialty chemicals used in materials science, dyes, and other niche applications.
- Rubber Additives: Beyond its direct use as a peptizer, it can be a precursor for synthesizing other specialized additives for rubber and polymer formulations.
Its application as a peptizer for natural and SBR rubbers further underscores its industrial relevance, simplifying processing by reducing melt viscosity.
Navigating the Supplier Landscape for CAS 13616-82-5
For procurement professionals, identifying a reliable supplier for 2,4-Dimethylbenzenethiol is crucial for ensuring product quality and supply chain continuity. Many B2B buyers look to China for its extensive chemical manufacturing capabilities. When seeking a manufacturer, it's important to request detailed specifications, including purity (e.g., 98% or higher), CAS number confirmation, and information on packaging and shipping terms (Incoterms like FOB, CFR, EXW). Partnering with established chemical suppliers who can provide comprehensive documentation, such as MSDS and Certificates of Analysis, is recommended. Companies like NINGBO INNO PHARMCHEM CO.,LTD. specialize in providing such intermediates, offering a direct channel to purchase high-quality chemicals from China.
The Advantage of a Direct Manufacturer Relationship
Purchasing directly from a manufacturer allows for better control over pricing, quality, and lead times. It eliminates intermediaries, potentially reducing costs and expediting delivery. When you need to buy 2,4-Dimethylbenzenethiol, engaging with a manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures you are dealing with a primary source. This direct relationship fosters better communication and support, essential for research-driven industries where timely access to specific chemical compounds is vital. Requesting a quote and inquiring about bulk purchase options can provide significant cost savings for larger R&D projects or production runs.
In summary, 2,4-Dimethylbenzenethiol (CAS 13616-82-5) is a versatile and valuable intermediate in organic synthesis. Its applications span pharmaceuticals, agrochemicals, and specialty chemicals, alongside its role as a rubber peptizer. For B2B buyers seeking a reliable source, exploring manufacturers in China, such as NINGBO INNO PHARMCHEM CO.,LTD., offers a pathway to consistent quality and competitive pricing, crucial for driving innovation and production forward.
Perspectives & Insights
Chem Catalyst Pro
“Understanding the Chemistry of 2,4-Dimethylbenzenethiol 2,4-Dimethylbenzenethiol is a derivative of thiophenol, featuring two methyl groups attached to the benzene ring at the 2 and 4 positions.”
Agile Thinker 7
“This functional group can participate in a wide array of chemical reactions, including nucleophilic substitutions, additions, and oxidations.”
Logic Spark 24
“Its properties, such as a melting point estimated at -30°C, a boiling point of 207-208 °C, and a density of 1.”