2-Bromo-1-(2-hydroxyphenyl)ethanone: Properties, Safety, and Sourcing for Your Chemical Needs

Navigating the landscape of chemical intermediates requires a thorough understanding of their properties, safe handling procedures, and reliable sourcing channels. 2-Bromo-1-(2-hydroxyphenyl)ethanone, identified by its CAS number 2491-36-3, is a compound of considerable interest in various chemical applications, particularly in organic synthesis and pharmaceutical intermediates synthesis. This article aims to provide essential information regarding its key characteristics, necessary safety precautions, and guidance on how to effectively source it.

The physical and chemical properties of 2-bromo-1-(2-hydroxyphenyl)ethanone are critical for its effective use. It typically appears as an off-white to pale yellow crystalline powder, with a melting point generally falling between 44-48°C. Its molecular formula is C₈H₇BrO₂, and it has a molecular weight of approximately 215.04 g/mol. Chemically, it features a reactive alpha-bromine atom positioned adjacent to a carbonyl group, making it highly susceptible to nucleophilic attack. The presence of a phenolic hydroxyl group also contributes to its reactivity and potential for modification. These attributes make it a versatile building block for synthesizing more complex organic molecules, including those vital for drug development.

Safety is a paramount concern when working with any chemical, and 2-bromo-1-(2-hydroxyphenyl)ethanone is no exception. It is classified as a corrosive solid and can be harmful if swallowed. It is also known to be a lachrymator, meaning it can cause eye irritation and tearing. Therefore, when handling this compound, it is imperative to adhere to strict safety protocols. This includes wearing appropriate personal protective equipment (PPE) such as chemical-resistant gloves, safety goggles or a face shield, and protective clothing. Work should be conducted in a well-ventilated area, preferably a fume hood, to avoid inhalation of dust or vapors. Always consult the Material Safety Data Sheet (MSDS) provided by the supplier for comprehensive safety information and emergency procedures. Understanding these safety aspects is crucial for anyone looking to buy or purchase this chemical.

Sourcing high-quality 2-bromo-1-(2-hydroxyphenyl)ethanone reliably is key to successful research and production. For those in need of this intermediate, it is highly recommended to partner with reputable chemical suppliers or manufacturers. Companies specializing in fine chemicals and intermediates, including many located in China, offer this compound. When selecting a supplier, consider factors such as purity specifications, consistency of supply, customer service, and availability of technical documentation like Certificates of Analysis (CoA) and MSDS. Working with a trusted manufacturer in China or a well-established supplier ensures that you receive material that meets your required standards for your organic synthesis and pharmaceutical intermediates synthesis projects.

In summary, 2-Bromo-1-(2-hydroxyphenyl)ethanone (CAS 2491-36-3) is a valuable intermediate with distinct properties and applications. By understanding its characteristics, adhering to safety guidelines, and sourcing it from reliable vendors, researchers and manufacturers can effectively leverage this compound to drive innovation in chemical synthesis and contribute to advancements in various industries, including pharmaceuticals.