In the realm of organic chemistry, certain molecules serve as foundational pillars for a vast array of complex syntheses. 2-Bromo-1,3-diisopropylbenzene (CAS: 57190-17-7) is one such indispensable organic building block, valued for its reactivity and structural versatility. This article explores its properties, applications, and the importance of sourcing it from reliable manufacturers.

Properties and Synthesis Utility of 2-Bromo-1,3-diisopropylbenzene

2-Bromo-1,3-diisopropylbenzene, with the molecular formula C12H17Br and molecular weight 241.17 g/mol, presents as a colorless liquid. Its key feature is the bromine atom attached to a benzene ring substituted with two isopropyl groups at the meta positions. This arrangement makes the bromine atom susceptible to nucleophilic substitution and, more importantly, to participation in metal-catalyzed cross-coupling reactions. These reactions are cornerstones of modern organic synthesis, enabling the formation of carbon-carbon and carbon-heteroatom bonds with high precision.

Key properties often sought by chemists include:

  • Reactivity: The aryl bromide functionality is highly amenable to transformations like Suzuki-Miyaura, Heck, Sonogashira, and Buchwald-Hartwig couplings.
  • Steric Hindrance: The isopropyl groups can influence regioselectivity and reactivity in certain reactions, offering unique synthetic opportunities.
  • Purity: For optimal results, especially in sensitive applications like pharmaceutical intermediate synthesis, procuring this compound with high purity (e.g., 97% min) is critical.

Applications Across Industries

The versatility of 2-Bromo-1,3-diisopropylbenzene translates into diverse applications:

  • Pharmaceutical Synthesis: It is a sought-after intermediate for constructing complex pharmaceutical molecules. Researchers looking to buy this for drug discovery or API synthesis will often search for its CAS number (57190-17-7) to ensure they are obtaining the correct precursor.
  • Materials Science: This building block can be incorporated into the synthesis of advanced materials, including organic electronic components, specialty polymers, and ligands for catalysis.
  • Fine Chemical Manufacturing: It serves as a precursor for various fine chemicals used in specialized industrial processes.
  • Research and Development: In academic and industrial R&D labs, it's a standard reagent for exploring new synthetic methodologies and creating novel chemical structures.

Sourcing and Purchasing Advice

When you need to buy 2-Bromo-1,3-diisopropylbenzene, prioritizing a reputable manufacturer is paramount. Look for suppliers who can guarantee high purity and provide comprehensive technical documentation, such as a Certificate of Analysis (CoA). Companies often inquire about '2-Bromo-1,3-diisopropylbenzene supplier China' or 'where to purchase 57190-17-7' to find reliable sources. Establishing a relationship with a manufacturer that offers consistent quality and competitive pricing for bulk orders ensures a stable supply for your ongoing projects.

In summary, 2-Bromo-1,3-diisopropylbenzene is an essential tool in the organic chemist's arsenal. Its strategic procurement from trusted sources empowers advancements in pharmaceuticals, materials science, and broader chemical research.