In the dynamic landscape of chemical synthesis, the availability of reliable and versatile intermediates is crucial for innovation and efficiency. 2-Bromobenzamide, identified by its CAS number 4001-73-4, is one such indispensable compound. At Ningbo Inno Pharmchem Co., Ltd., we specialize in providing high-quality chemical intermediates, and 2-Bromobenzamide is a cornerstone of our offerings for the pharmaceutical and fine chemical industries.

The Chemical Identity of 2-Bromobenzamide

2-Bromobenzamide is an organic compound with the molecular formula C7H6BrNO and a molecular weight of 200.03300. It typically presents as a beige powder, with a melting point in the range of 160-162°C. This solid form, combined with its stability under recommended storage conditions (sealed, dry, room temperature), makes it a practical reagent for laboratory and industrial use. The strategic placement of the bromine atom and the amide group on the benzene ring provides reactive sites that are highly valuable in organic synthesis.

Applications in Pharmaceutical Development

The pharmaceutical industry heavily relies on precise and effective synthetic routes to develop new drugs. 2-Bromobenzamide serves as a vital pharmaceutical intermediate, enabling the construction of complex molecular scaffolds essential for therapeutic activity. Its participation in microwave-assisted one-pot syntheses, for example, allows for the efficient creation of substituted 3-(phenylmethylene)isoindolin-1-ones. These heterocyclic structures are frequently incorporated into drug molecules due to their diverse biological activities.

Furthermore, the compound’s utility in palladium-catalyzed reactions is significant. These advanced catalytic methods are indispensable for creating intricate carbon-carbon and carbon-heteroatom bonds, which are fundamental to drug discovery and development. The synthesis of phenanthridinones, a class of compounds with reported potential in medicinal chemistry, often involves 2-Bromobenzamide as a key precursor. The ability to procure high-purity 2-Bromobenzamide is therefore critical for ensuring the success of these sensitive synthetic procedures.

In addition to its direct role in synthesizing active pharmaceutical ingredients (APIs), 2-Bromobenzamide is also used in the creation of specialized ligands, such as water-soluble iminophosphorane ligands. These ligands can be employed in catalysis, facilitating more efficient and selective chemical reactions, which in turn can streamline pharmaceutical manufacturing processes.

Sourcing and Quality Assurance from Ningbo Inno Pharmchem

For researchers and manufacturers, securing a reliable source for critical intermediates like 2-Bromobenzamide is paramount. Ningbo Inno Pharmchem Co., Ltd. is dedicated to maintaining the highest standards of quality and purity for all its chemical products. When looking to 'purchase 2-Bromobenzamide' or find '2-Bromobenzamide suppliers', it is essential to partner with companies that prioritize product integrity and provide comprehensive documentation, such as certificates of analysis. This ensures that your projects benefit from materials that meet exact specifications, contributing to reproducible and scalable results.

In essence, 2-Bromobenzamide (CAS 4001-73-4) is a highly versatile and critical organic intermediate. Its well-defined chemical properties and its extensive applications in pharmaceutical synthesis and fine chemical production highlight its indispensable role in the chemical industry. Ningbo Inno Pharmchem Co., Ltd. is committed to supporting scientific progress by providing this essential compound with unwavering quality and reliability.