In the vast landscape of chemical compounds, certain molecules serve as foundational elements for innovation and production. 2-Hydroxyacetamide (CAS: 598-42-5), commonly known as Glycolamide, is one such compound. Its relatively simple structure belies its significant utility as a chemical intermediate, finding applications in sectors ranging from pharmaceuticals to specialty chemicals. Understanding its synthesis, inherent properties, and industrial applications is key for any professional involved in chemical sourcing and utilization.

Synthesis and Production of 2-Hydroxyacetamide

The synthesis of 2-Hydroxyacetamide typically involves the ammonolysis of ethyl glycolate. This process, where ammonia reacts with ethyl glycolate, yields 2-Hydroxyacetamide and ethanol. The reaction conditions, such as temperature, pressure, and reactant ratios, are carefully controlled by manufacturers to optimize yield and purity. For industrial scale production, efficient separation and purification techniques are employed to obtain the desired crystalline powder form. As a prominent chemical manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. employs advanced synthesis and purification methodologies to ensure the consistent quality of our 2-Hydroxyacetamide.

Key Physicochemical Properties

The practical application of any chemical intermediate is heavily influenced by its physical and chemical properties. 2-Hydroxyacetamide is characterized by:

  • Appearance: White to off-white or light yellow crystalline powder. This consistent appearance is a good initial indicator of product quality for buyers.
  • Melting Point: Approximately 118-120°C. This relatively sharp melting point suggests a well-defined crystalline structure.
  • Solubility: Highly soluble in water (413.5g/L at 25°C), indicating its suitability for reactions conducted in aqueous media or for applications where water solubility is important.
  • Chemical Reactivity: Possesses a reactive hydroxyl group and an amide group, making it a versatile intermediate for various organic transformations.

These properties make it an attractive option for chemists looking to buy 2-Hydroxyacetamide for its reactive potential and ease of handling.

Industrial Relevance and Applications

The versatility of 2-Hydroxyacetamide stems from its ability to act as a precursor in a multitude of chemical synthesis pathways. Its primary roles include:

  • Organic Synthesis Intermediate: It's a building block for creating more complex organic molecules. Researchers and manufacturers often purchase 2-Hydroxyacetamide for its role in constructing specific carbon skeletons or introducing functional groups.
  • Pharmaceutical and Agrochemical Research: As a potential starting material or intermediate, it contributes to the development of new drugs and agricultural chemicals.
  • Material Science: In some instances, it can be used in the modification or synthesis of polymers and advanced materials.

For those seeking to source this valuable compound, understanding the market and identifying reliable suppliers is crucial. As a leading chemical supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. offers high-purity 2-Hydroxyacetamide, coupled with competitive pricing and dependable logistics. We are committed to supporting your research and manufacturing needs with quality chemical intermediates.

Partner for Your Chemical Intermediate Needs

If your organization requires 2-Hydroxyacetamide for synthesis or research, consider NINGBO INNO PHARMCHEM CO.,LTD. as your trusted partner. We provide a reliable supply of this essential chemical intermediate. Inquire today for the latest pricing and availability, and discover how our commitment to quality and service can benefit your operations.