3,5-Dihydroxybenzoic Acid (3,5-DHBA), CAS 99-10-5, is a compound gaining recognition not only for its role in organic synthesis but also for its intriguing connections to human health and diet. Often called alpha-Resorcylic acid, this organic molecule serves as a critical link between dietary intake, gut health, and metabolic processes. This article explores the multifaceted nature of 3,5-DHBA, focusing on its discovery as a dietary biomarker and its implications for health insights and medicinal applications.

Dietary Connections and Biomarker Significance

Research has established a strong association between 3,5-Dihydroxybenzoic Acid and the consumption of whole-grain foods, particularly wheat and rye. It is identified as a primary metabolite of alkylresorcinols, which are naturally occurring phenolic lipids found in the bran of these grains. Consequently, the presence and levels of 3,5-DHBA in human urine and plasma can serve as a valuable biomarker for assessing whole-grain intake. This makes it an important tool in nutritional science and public health research, helping to understand dietary patterns and their impact on well-being. The ability to accurately quantify 3,5-DHBA relies on precise analytical methods, often employed by companies providing specialized testing services, and the availability of high-purity 3,5-Dihydroxybenzoic Acid from reliable manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. for calibration and reference.

Health Implications and Potential Therapeutic Uses

Beyond its role as a biomarker, 3,5-Dihydroxybenzoic Acid is being investigated for its potential health benefits. Studies suggest it may possess antioxidant and anti-inflammatory properties, making it a candidate for developing new therapeutic agents. Its interaction with the hydroxycarboxylic acid receptor 1 (HCA1) is of particular interest, as it has been shown to inhibit lipolysis, potentially offering a mechanism for managing dyslipidemia and metabolic disorders. As a compound that can be produced in the gastrointestinal tract by microbial breakdown, its levels can also indicate gut microbiome status, with elevated levels potentially suggesting dysbiosis. This opens avenues for its use in functional medicine and personalized health assessments.

Industrial Importance and Supply Chain

The consistent availability of high-quality 3,5-Dihydroxybenzoic Acid is crucial for both research and industrial applications. As a key intermediate in organic synthesis, it supports the development of pharmaceuticals and specialized materials. NINGBO INNO PHARMCHEM CO.,LTD., as a leading 3,5-Dihydroxybenzoic Acid supplier in China, ensures that this compound is accessible to researchers and industries worldwide. Their commitment to producing high-purity material, backed by robust manufacturing processes, underpins its use in critical applications, from laboratory analysis to the synthesis of complex chemical compounds.

In essence, 3,5-Dihydroxybenzoic Acid represents a vital link between our diet, our health, and the advancement of chemical sciences.