The exploration of novel chemical compounds with significant biological activities is a cornerstone of modern research, particularly in medicinal chemistry and agriculture. 3-Chloro-5-(trifluoromethyl)pyridine (CAS: 85148-26-1) stands out as a compound with intriguing biological properties and broad research applications. As a leading supplier of high-purity intermediates from China, we are pleased to share insights into the potential of this versatile molecule.

Biological Activity Profile

Research has indicated that derivatives of 3-Chloro-5-(trifluoromethyl)pyridine exhibit promising biological activities. These include:

  • Anticancer Potential: Studies suggest that certain derivatives of this compound possess cytotoxic effects against various cancer cell lines. The trifluoromethyl and chloro substituents can influence molecular interactions with biological targets, making them candidates for anticancer drug development.
  • Anti-inflammatory Properties: Evidence points to potential anti-inflammatory effects in related pyridine structures, suggesting that this compound could serve as a lead structure for developing new therapeutic agents for inflammatory conditions.
  • Antimicrobial Effects: Preliminary research has hinted at antibacterial properties against certain strains, opening avenues for exploring novel antimicrobial therapies.
  • Agrochemical Utility: Its application as an intermediate in agrochemicals is well-established, with derivatives showing herbicidal and fungicidal properties crucial for crop protection.

The trifluoromethyl group's contribution to lipophilicity and metabolic stability, along with the specific electronic modulation by the chlorine atom, are key factors underlying these biological effects. These characteristics allow the molecule to interact effectively with biological membranes and target proteins.

Research Applications and Synthetic Utility

Beyond its direct biological implications, 3-Chloro-5-(trifluoromethyl)pyridine is a highly valuable building block in organic synthesis. Its facile incorporation into complex molecular architectures makes it a favorite among medicinal chemists and synthetic organic chemists. Researchers utilize it to:

  • Synthesize novel fluorinated pharmaceuticals.
  • Develop advanced agrochemical compounds.
  • Create functional materials with tailored electronic or optical properties.
  • Explore structure-activity relationships (SAR) to optimize compound efficacy.

The ability to purchase high-purity 3-Chloro-5-(trifluoromethyl)pyridine (≥98.0%) from a reliable China manufacturer like us is critical for researchers who depend on consistent quality for their experimental outcomes. Our commitment ensures that your research is supported by dependable, high-grade materials.

Partner with Us for Your Research Needs

If your research requires 3-Chloro-5-(trifluoromethyl)pyridine or its derivatives, we are your trusted source. We offer competitive pricing and flexible packaging options to suit research-scale and industrial demands. Contact us today to inquire about availability, request a quotation, and buy 3-Chloro-5-(trifluoromethyl)pyridine to advance your scientific endeavors. Our aim is to facilitate groundbreaking discoveries through the supply of exceptional chemical intermediates.