In the complex world of chemical synthesis and research, understanding the properties of key compounds is vital. 5-Amino-1MQ, a potent inhibitor of Nicotinamide N-methyltransferase (NNMT), has garnered significant attention for its role in metabolic regulation and cellular energy. As a specialized manufacturer, we are at the forefront of producing high-quality 5-Amino-1MQ, offering insights into its chemical characteristics and research applications.

The Chemical Identity of 5-Amino-1MQ

5-Amino-1MQ is chemically known as 5-Amino-1-methylquinolinium. Its molecular formula is C₁₀H₁₁N₂⁺, with a molecular weight of approximately 159.21 g/mol. Typically supplied as a salt (e.g., chloride), this compound is characterized by its quinolinium core, featuring an amino group at the 5-position and a methyl group at the 1-position. This specific molecular structure is crucial for its activity as an NNMT inhibitor, allowing it to interact with the enzyme's active site.

Mechanism of Action: NNMT Inhibition at the Molecular Level

The primary function of 5-Amino-1MQ is to inhibit the NNMT enzyme. NNMT catalyzes the N-methylation of nicotinamide, a reaction that consumes S-adenosylmethionine (SAM) as a methyl donor and yields 1-methylnicotinamide. This process indirectly reduces the availability of nicotinamide for conversion into Nicotinamide Adenine Dinucleotide (NAD⁺), a critical coenzyme for cellular energy metabolism and repair. By blocking NNMT, 5-Amino-1MQ effectively:

  • Preserves Nicotinamide: Increases the pool of nicotinamide available for NAD⁺ synthesis.
  • Enhances NAD⁺ Levels: Directly contributes to higher intracellular NAD⁺ concentrations, supporting mitochondrial function and sirtuin activity.
  • Modulates Methylation: Influences cellular methylation processes, which are linked to various metabolic functions and gene regulation.

This precise molecular action underpins its potential in research areas such as metabolic health, fat metabolism, and longevity studies.

Manufacturer's Commitment to Quality and Purity

As a dedicated manufacturer, our focus is on producing 5-Amino-1MQ that meets the highest standards for research use. We understand that the purity and consistency of chemical compounds are critical for reliable scientific outcomes. Our production processes involve:

  • Advanced Synthesis Techniques: Utilizing precise chemical synthesis methods to achieve the desired molecular structure and purity.
  • Rigorous Quality Control: Implementing multi-stage quality checks, including High-Performance Liquid Chromatography (HPLC) analysis, to verify identity and purity (typically ≥99%).
  • Comprehensive Documentation: Providing Certificates of Analysis (COA) for each batch, detailing purity, identity, and other critical parameters.
  • Reliable Supply Chain: Ensuring a consistent and stable supply chain to meet the ongoing needs of researchers and laboratories worldwide.

When you choose to buy 5-Amino-1MQ from us, you are investing in a product that is manufactured with scientific integrity and a commitment to excellence. Our competitive pricing and dependable delivery further support your research endeavors.

Research Applications and Future Directions

The research potential of 5-Amino-1MQ is vast, spanning areas from weight management and metabolic disorders to cellular aging and energy production. As a manufacturer, we are proud to supply a compound that facilitates this critical scientific inquiry.

Conclusion: Your Trusted Partner for 5-Amino-1MQ

Understanding the chemical properties and mechanism of action of 5-Amino-1MQ is key to its effective use in research. As a specialized manufacturer, we are committed to providing researchers with access to high-purity, consistently produced 5-Amino-1MQ. By partnering with us, you gain a reliable source for this important research chemical, ensuring the quality and accuracy of your scientific explorations into metabolic health and cellular function.