Acetyl Ketene, also known as Diketene and identified by CAS number 674-82-8, is a vital chemical intermediate widely used across various industrial sectors. Its unique reactivity, stemming from its strained four-membered ring structure, makes it a valuable building block for organic synthesis. However, this reactivity also necessitates a thorough understanding of its properties, associated hazards, and the implementation of strict safe handling procedures. As a dedicated manufacturer and supplier of fine chemicals, we believe in empowering our clients with this knowledge.

Key Properties of Acetyl Ketene:

  • Appearance: Typically a colorless to pale yellow liquid.
  • Odor: Possesses a pungent or disagreeable odor.
  • Chemical Formula: C4H4O2
  • Molecular Weight: 84.07 g/mol
  • Boiling Point: Approximately 69-70 °C at 100 mmHg.
  • Density: Around 1.09 g/mL at 25 °C.
  • Flammability: Highly flammable with a low flash point (95 °F / 34 °C), requiring careful management of ignition sources.

Industrial Applications:

Acetyl Ketene serves as a crucial intermediate in several industries:

  • Pharmaceutical Synthesis: Used to synthesize various pharmaceutical intermediates, including acetoacetic esters and acetoacetanilides, which are foundational for many drugs.
  • Paper Industry: Acts as a sizing agent to improve paper printability and water resistance.
  • Dye and Pigment Production: A key precursor in the synthesis of azo dyes and pigments.
  • Agrochemicals: Utilized in the production of certain insecticides and other crop protection chemicals.

Hazards and Safety Precautions:

Due to its reactive nature, Acetyl Ketene presents several hazards that must be managed:

  • Reactivity and Polymerization: It can undergo spontaneous polymerization, especially when heated or in the presence of acids, bases, or amines. This polymerization can be violent and generate significant heat or pressure.
  • Toxicity: Acetyl Ketene is toxic and can be harmful if inhaled, ingested, or absorbed through the skin. It is also a lachrymator, causing eye irritation.
  • Flammability: As a flammable liquid, it poses a fire risk. Vapors can form explosive mixtures with air and may travel to ignition sources.

Safe Handling and Storage:

To ensure safe use, the following precautions are recommended:

  • Ventilation: Handle in well-ventilated areas, preferably under a fume hood.
  • Ignition Sources: Keep away from heat, sparks, open flames, and static discharge. Use non-sparking tools and explosion-proof equipment.
  • Personal Protective Equipment (PPE): Always wear appropriate PPE, including chemical-resistant gloves, safety goggles or face shield, and protective clothing. Respiratory protection (e.g., a respirator with an organic vapor cartridge) is essential if ventilation is inadequate.
  • Storage: Store in tightly sealed containers in a cool (2-8°C), dry, and well-ventilated area, away from incompatible materials. Stainless steel or aluminum containers are preferred.
  • Incompatibilities: Avoid contact with strong acids, bases, amines, oxidizing agents, and water, as these can trigger hazardous reactions.

As a direct manufacturer, we prioritize the safety of our customers. We ensure our Acetyl Ketene is supplied with proper stabilization and detailed safety information. If you are looking to purchase Acetyl Ketene for industrial applications, we are your trusted supplier, offering quality products and expert guidance on safe handling. Contact us today to learn more or to request a quote.