Achieving High Selectivity: EGTA for Precise Metal Ion Control
In scientific disciplines ranging from biochemistry to analytical chemistry, precise control over metal ion concentrations is often the key to unlocking accurate and meaningful results. Ethylenebis(oxyethylenenitrilo)tetraacetic Acid (EGTA, CAS 67-42-5) is a specialized chelating agent that excels in providing this control, particularly with calcium ions. As a trusted supplier and manufacturer of fine chemicals, we understand the demand for high-purity, selectively acting compounds like EGTA.
EGTA is a white crystalline powder (C14H24N2O10, MW 380.35) that stands out due to its significantly higher affinity for calcium (Ca2+) compared to magnesium (Mg2+). While EDTA is a powerful general-purpose chelator, it chelates both calcium and magnesium with similar strength. This lack of selectivity can be problematic in experiments where magnesium is essential for enzyme function or cellular stability, and only calcium needs to be controlled. EGTA's design allows it to effectively 'buffer' calcium levels, ensuring that free calcium concentrations are minimized without depleting essential magnesium.
This high selectivity makes EGTA indispensable in several critical applications. In physiological studies, it is used to mimic conditions of calcium deficiency or to block calcium-dependent cellular events. For researchers in academic institutions or pharmaceutical companies looking to buy EGTA, this specificity translates directly into more reliable data and clearer experimental outcomes. Our company, as a manufacturer in China, ensures that our EGTA product meets stringent purity standards, typically exceeding 99%, to guarantee this critical selectivity.
Applications include studies of ion channels, receptor binding assays, and protein purification where calcium ions might interfere. In enzymatic assays, EGTA can be used to maintain a low calcium environment, ensuring that only calcium-independent enzymatic activities are measured, or to precisely titrate calcium levels to study calcium-dependent enzymes. The ability to purchase EGTA at a competitive price from a reliable supplier is crucial for cost-effective research and development.
We are committed to providing the scientific community with the tools they need for precision work. Our supply of Ethylenebis(oxyethylenenitrilo)tetraacetic Acid is backed by rigorous quality control and a stable manufacturing process. If your work demands precise metal ion control, especially regarding calcium, we encourage you to consider EGTA. Contact us today to inquire about EGTA price, bulk quantities, and the benefits of sourcing from a leading Chinese chemical supplier.
Perspectives & Insights
Quantum Pioneer 24
“Contact us today to inquire about EGTA price, bulk quantities, and the benefits of sourcing from a leading Chinese chemical supplier.”
Bio Explorer X
“In scientific disciplines ranging from biochemistry to analytical chemistry, precise control over metal ion concentrations is often the key to unlocking accurate and meaningful results.”
Nano Catalyst AI
“Ethylenebis(oxyethylenenitrilo)tetraacetic Acid (EGTA, CAS 67-42-5) is a specialized chelating agent that excels in providing this control, particularly with calcium ions.”