1-Bromo-2-iodobenzene (CAS 583-55-1) stands out as a highly valuable intermediate in the realm of modern organic synthesis. Its unique structural attributes, featuring both bromine and iodine substituents on an aromatic ring, endow it with exceptional versatility and reactivity. This makes it a cornerstone for chemists aiming to construct complex molecular architectures across various industries. As a leading manufacturer and supplier, we provide this crucial building block to support your groundbreaking research and development efforts.

One of the most significant applications of 1-Bromo-2-iodobenzene lies in its participation in various palladium-catalyzed cross-coupling reactions. These reactions are pivotal for forming carbon-carbon bonds, a fundamental process in the synthesis of pharmaceuticals and agrochemicals. For instance, in the Suzuki-Miyaura coupling, it readily reacts with organoboron compounds to form biaryl systems, which are prevalent in many drug molecules. Similarly, the Sonogashira coupling allows for the introduction of alkynyl groups, enabling the synthesis of conjugated systems crucial for advanced materials and certain pharmaceutical agents. Researchers often seek to buy such intermediates to explore novel synthetic routes.

The differential reactivity of the halogen atoms in 1-Bromo-2-iodobenzene offers unique synthetic opportunities. The carbon-iodine bond is generally more labile and reactive in oxidative addition steps of catalytic cycles compared to the carbon-bromine bond. This allows for selective functionalization. A chemist can, for example, first perform a cross-coupling reaction at the iodo position and then carry out a different transformation at the bromo position. This stepwise approach is invaluable for creating highly substituted aromatic compounds with precise regiochemistry, a capability that is often challenging to achieve otherwise. This precision is vital for product formulators aiming for specific properties and efficacy.

Beyond cross-coupling, 1-Bromo-2-iodobenzene is also instrumental in the synthesis of organometallic reagents, such as Grignard reagents or organolithium compounds, which can then be used in a wide array of nucleophilic addition and substitution reactions. This expands its utility into the creation of diverse organic frameworks. The compound also finds applications in materials science, where it can be incorporated into the synthesis of polymers, liquid crystals, and organic electronic materials, leveraging its aromatic structure and potential for further functionalization. For those looking to source this compound, understanding the application landscape helps in justifying the purchase and the importance of its consistent availability from a reliable supplier.

We are committed to being your trusted source for high-quality 1-Bromo-2-iodobenzene. Our state-of-the-art manufacturing facilities ensure that we can supply this intermediate in quantities ranging from research-scale to industrial bulk. We invite you to contact us for a quote and to explore how our consistent quality and competitive pricing can benefit your projects. Let us be your partner in driving innovation through advanced chemical synthesis.