Understanding the synthesis and diverse applications of chemical compounds is crucial for advancing scientific research and industrial processes. 1-Ethynyl-1-cyclohexanol (CAS 78-27-3) is one such compound, valued for its unique chemical structure and its utility across various sectors. As a prominent manufacturer and supplier, we offer insights into its synthesis pathways and key applications, inviting you to purchase this essential chemical.

The synthesis of 1-Ethynyl-1-cyclohexanol typically involves the addition of acetylene to cyclohexanone. Various methods exist, often employing strong bases or organometallic reagents to generate the acetylide anion, which then nucleophilically attacks the carbonyl carbon of cyclohexanone. For instance, the reaction of cyclohexanone with sodium acetylide in liquid ammonia, followed by acidic work-up, is a classical approach. More contemporary methods might involve catalytic ethynylation reactions using transition metal catalysts or improved procedures with reagents like the potassium salt of tert-amyl alcohol, which can offer higher yields and better operational simplicity.

The chemical properties of 1-Ethynyl-1-cyclohexanol, particularly the presence of both an ethynyl group and a hydroxyl group, make it a versatile building block in organic synthesis. Its applications span several key areas:

1. Silicone Inhibitor: It is widely used as a platinum catalyst inhibitor in silicone formulations. This function is vital for controlling the curing rate of addition-cure silicones, extending their pot life and ensuring processability. This is a significant application for manufacturers in the rubber and sealant industries.

2. Organic Synthesis Intermediate: The compound serves as a crucial intermediate for synthesizing more complex organic molecules. Its functional groups allow for reactions such as click chemistry, Sonogashira coupling, and various functional group transformations, making it valuable in pharmaceutical and fine chemical production.

3. Material Science: Its unique structure lends itself to applications in advanced materials, including potential use in polymers and resins where specific properties related to its acetylenic and hydroxyl functionalities are desired.

For procurement managers and researchers looking to buy 1-Ethynyl-1-cyclohexanol, selecting a reputable manufacturer is essential. Our commitment to producing high-purity (≥99%) material ensures that you receive a product suitable for demanding applications. We offer competitive pricing and reliable supply from our China-based operations. Contact us today to discuss your needs and make a purchase that will support your chemical synthesis and formulation requirements.