In the intricate world of organic chemistry, reagents that offer both versatility and stability are highly prized. Bis(pinacolato)diborane (CAS 78183-34-3) fits this description perfectly, serving as a critical building block in numerous synthetic pathways. For research scientists and formulators, understanding its synthesis, diverse applications, and the importance of quality assurance from a reliable supplier is key to successful outcomes. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-grade Bis(pinacolato)diborane to meet these demands.

Bis(pinacolato)diborane is typically synthesized through a process involving tetrakis(dimethylamino)diboron and pinacol in the presence of an acid. This method yields a stable, white crystalline solid that is soluble in common organic solvents like tetrahydrofuran, dichloromethane, and toluene, but insoluble in water. Its physical properties, including a melting point around 137-140 °C, make it a manageable reagent for laboratory and industrial use.

The utility of Bis(pinacolato)diborane spans across several crucial fields. In organic synthesis, it is a premier reagent for the preparation of pinacol boronic esters. These esters are then readily employed in palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, allowing for the efficient formation of carbon-carbon bonds. This capability is fundamental in the synthesis of pharmaceuticals, agrochemicals, and advanced materials, where precise molecular construction is vital.

For R&D scientists working on new drug candidates, Bis(pinacolato)diborane is an indispensable tool for creating complex pharmaceutical intermediates. Its use in forming arylboronic esters facilitates the introduction of aryl groups into target molecules, a common strategy in medicinal chemistry. The reliability of this reagent directly impacts the efficiency and yield of these syntheses.

Quality assurance is non-negotiable when it comes to chemical intermediates. NINGBO INNO PHARMCHEM CO.,LTD. ensures that our Bis(pinacolato)diborane, supplied at a minimum purity of 98%, is manufactured under strict quality control protocols. As a direct manufacturer, we oversee the entire production process, guaranteeing lot-to-lot consistency and purity. This commitment provides peace of mind for our B2B clients who rely on us for their critical material needs.

We understand that purchasing chemical reagents involves more than just the product itself; it includes reliable supply, competitive pricing, and excellent customer service. If you are looking to buy Bis(pinacolato)diborane, we encourage you to contact us for a quote and to learn more about our comprehensive offerings. Our team is ready to assist you in securing this vital reagent for your synthetic endeavors.