Bromocresol Green in Albumin Assays: A Diagnostic Cornerstone
The accurate quantification of serum albumin is a vital component of routine medical diagnostics, providing critical insights into liver function, kidney health, and overall nutritional status. In this diagnostic landscape, Bromocresol Green (BCG), a well-established pH indicator, emerges as a key reagent. Known for its ability to form colored complexes with specific proteins, particularly albumin, under controlled pH conditions, BCG has become a cornerstone in clinical chemistry laboratories worldwide. Sourcing high-quality Bromocresol Green from reputable manufacturers is crucial for ensuring the reliability of these diagnostic tests.
Bromocresol Green, identified by its CAS number 76-60-8, functions as a dye that binds selectively to albumin in serum samples. This binding event is pH-dependent, typically occurring in a slightly acidic environment. When albumin molecules bind to BCG, they induce a change in the dye's spectral properties, specifically its absorbance maximum. This alteration in light absorption can be precisely measured using spectrophotometry, allowing for the indirect but accurate determination of albumin concentration. Laboratories often seek to buy Bromocresol Green in bulk to meet the demands of high-throughput diagnostic testing.
The diagnostic utility of Bromocresol Green is amplified by its predictable performance and the availability of standardized assay protocols. While the chemical itself is a potent pH indicator with a transition range of 3.8 to 5.4, its application in albumin assays relies on its protein-binding affinity rather than its pH-indicating function. However, maintaining the correct pH during the assay is critical for the specific binding of albumin to BCG, thus highlighting the compound's dual nature. Researchers and lab managers frequently inquire about the Bromocresol Green price from manufacturers to budget for these essential diagnostic reagents.
For clinical laboratories to ensure the accuracy and reproducibility of albumin assays, the purity and consistency of the Bromocresol Green used are paramount. NINGBO INNO PHARMCHEM CO.,LTD. prides itself on being a reliable manufacturer and supplier of high-purity chemicals. Our Bromocresol Green is produced to exacting standards, ensuring that each batch provides optimal performance in albumin quantification. We understand the critical nature of diagnostic reagents and are dedicated to supporting healthcare professionals by providing a dependable source for this vital chemical.
We encourage all diagnostic laboratories and healthcare providers to consider NINGBO INNO PHARMCHEM CO.,LTD. for their Bromocresol Green requirements. Our commitment to quality, competitive pricing, and consistent supply chain makes us an ideal partner. Contact us today to learn more about our products and to request a quote for your laboratory's needs, ensuring you have access to the high-quality Bromocresol Green essential for accurate patient diagnostics.
Perspectives & Insights
Logic Thinker AI
“Known for its ability to form colored complexes with specific proteins, particularly albumin, under controlled pH conditions, BCG has become a cornerstone in clinical chemistry laboratories worldwide.”
Molecule Spark 2025
“Sourcing high-quality Bromocresol Green from reputable manufacturers is crucial for ensuring the reliability of these diagnostic tests.”
Alpha Pioneer 01
“Bromocresol Green, identified by its CAS number 76-60-8, functions as a dye that binds selectively to albumin in serum samples.”