In the dynamic world of chemical synthesis and pharmaceutical development, access to reliable, high-quality intermediates is non-negotiable. 3-Ethynylthiophene (CAS: 67237-53-0) is a prime example of such a crucial building block. This article serves as a comprehensive guide for procurement managers and researchers seeking to purchase this versatile compound, highlighting its importance, applications, and how to secure a dependable supply from reputable manufacturers.

Why Choose 3-Ethynylthiophene?

3-Ethynylthiophene is a heterocyclic organic compound with the molecular formula C6H4S and a molecular weight of 108.16 g/mol. It is characterized by a thiophene ring appended with an ethynyl group. This unique combination offers:

  • Versatile Reactivity: The terminal alkyne group readily participates in a wide range of chemical transformations, including click chemistry, Sonogashira coupling, and polymerization.
  • Structural Versatility: The thiophene moiety is a common and valuable scaffold in many functional molecules and pharmaceuticals.
  • High Purity: Typically available at a minimum purity of 97%, ensuring reliable results in complex synthetic routes.
  • Ease of Handling: Its liquid form at room temperature (colorless to yellow to orange) simplifies measurement and addition in reaction setups.

Key Applications Driving Demand

The demand for 3-Ethynylthiophene is driven by its critical role in several advanced sectors:

  1. Synthesis Materials Intermediates: It's a go-to building block for creating advanced polymers, specialty chemicals, and novel functional materials. Its incorporation allows for precise molecular engineering, leading to materials with tailored properties for high-tech applications.
  2. Pharmaceutical Raw Intermediates: The pharmaceutical industry relies on 3-Ethynylthiophene for synthesizing new drug candidates and APIs. Its structure is amenable to modification, facilitating the development of compounds with specific biological activities.
  3. Organic Electronics: Researchers in organic electronics utilize it to synthesize organic semiconductors for use in OLEDs, organic solar cells, and flexible displays, pushing the boundaries of electronic device performance.

Where to Buy 3-Ethynylthiophene: Your Procurement Strategy

When you decide to buy 3-ethynylthiophene, several factors are critical for a successful procurement:

  • Reputable Manufacturers: Look for established manufacturers with a proven track record in producing high-purity intermediates. Suppliers in China are often a strong choice due to their production scale and competitive pricing.
  • Product Specification: Always confirm the purity (e.g., 97% min.), CAS number (67237-53-0), molecular formula, and molecular weight. Requesting a Certificate of Analysis (CoA) is essential.
  • Competitive 3-Ethynylthiophene Price: Compare quotes from multiple suppliers, keeping in mind that the lowest price should not compromise quality or reliability. Consider bulk purchase options for better cost-effectiveness.
  • Lead Times and Availability: Understand the supplier's production capacity and typical lead times to ensure timely delivery for your projects.
  • Customer Service: A responsive and knowledgeable customer service team can be invaluable, especially when dealing with specialized chemicals. Inquiring about free samples is a good initial step to assess quality.

Conclusion

3-Ethynylthiophene (CAS: 67237-53-0) is an indispensable intermediate for modern chemical synthesis and pharmaceutical innovation. By understanding its properties, applications, and strategic procurement considerations, R&D professionals and purchasing managers can confidently source this vital compound. Partnering with a reliable manufacturer or supplier ensures you receive high-quality 3-ethynylthiophene, driving your projects forward with efficiency and success.