For academic and industrial research chemists, access to reliable chemical reagents and building blocks is the cornerstone of successful experimentation. 5-Chloro-2-methylthiophenol (CAS 18858-06-5) is a valuable compound in this regard, often employed in various synthesis projects. This guide aims to assist researchers in understanding its applications and making informed purchasing decisions.

Understanding the Research Value of 5-Chloro-2-methylthiophenol

5-Chloro-2-methylthiophenol, also known as 5-chloro-2-methylbenzenethiol, is a functionalized aromatic compound that provides a versatile platform for chemical transformations. Its unique combination of a thiol group, a chlorine substituent, and a methyl group on the benzene ring makes it an attractive starting material for:

  • Novel Molecule Synthesis: Researchers utilize it to construct new organic molecules, including potential drug candidates, agrochemicals, and advanced materials.
  • Methodology Development: Its reactivity can be explored in developing new synthetic routes or optimizing existing ones, particularly reactions involving sulfur chemistry or halogenated aromatics.
  • Structure-Activity Relationship (SAR) Studies: In medicinal chemistry research, modifications around the thiophenol core can help elucidate how molecular structure influences biological activity.
  • Catalyst Ligand Synthesis: Certain sulfur-containing organic compounds are used as ligands in transition metal catalysis, and this intermediate could potentially be a precursor for such applications.

Key Considerations When Buying for Research

When purchasing 5-Chloro-2-methylthiophenol for laboratory use, researchers should pay attention to:

  • Purity Levels: While research applications might tolerate slightly lower purity than GMP pharmaceutical production, higher purity (e.g., 95% or above) is generally preferred to ensure reliable and reproducible experimental results. Always check the supplier's stated purity.
  • Quantity and Packaging: Available pack sizes often range from grams to kilograms. Researchers should select a quantity that matches their experimental scale, considering the compound's shelf life and storage conditions.
  • Supplier Reputation: Opt for reputable chemical suppliers known for quality and service. This often means purchasing from established chemical distributors or directly from manufacturers who cater to the research community.
  • Safety Information: Always review the Safety Data Sheet (SDS) provided by the supplier. This document contains crucial information on safe handling, storage, potential hazards, and emergency procedures.

Finding Reliable Suppliers

For researchers in need of 5-Chloro-2-methylthiophenol, several avenues exist for procurement. Many global chemical suppliers offer this compound. For those looking for competitive pricing and efficient delivery, investigating suppliers based in China can be advantageous. Companies specializing in fine chemicals and custom synthesis often maintain comprehensive catalogs and can readily supply such intermediates. When you need to buy this chemical, always compare specifications, pricing, and delivery times from different vendors.

By understanding the applications and carefully selecting a supplier, researchers can effectively leverage 5-Chloro-2-methylthiophenol (CAS 18858-06-5) to drive their scientific investigations forward.