N,N'-Carbonyldiimidazole (CDI): A Safer, Efficient Tool for Organic Transformations
The pursuit of efficient and safe chemical synthesis is a constant endeavor in scientific and industrial circles. N,N'-Carbonyldiimidazole (CDI) has firmly established itself as a premier reagent, offering a potent combination of reactivity and user-friendliness for a wide range of organic transformations. As a dedicated manufacturer and supplier of specialized chemicals, we are proud to offer high-purity CDI, empowering chemists to achieve superior results.
CDI is primarily utilized as a coupling agent, adept at activating carboxylic acids to facilitate the formation of essential chemical linkages such as amides, esters, ureas, and carbamates. Its mechanism involves reacting with a carboxylic acid to form an acyl imidazole, which then readily reacts with various nucleophiles. This process is vital in numerous synthetic pathways, including the intricate construction of peptides, which are foundational to many pharmaceutical research and development efforts. The reliability of CDI is further enhanced by its availability from trusted manufacturers.
One of the most significant benefits of CDI is its advantage over hazardous reagents like phosgene. Phosgene, historically used for similar chemical transformations, is a dangerous gas requiring stringent safety protocols. CDI, conversely, is a stable, crystalline solid that is significantly safer to handle and store, reducing operational risks in both laboratory and industrial settings. This improved safety profile makes it an attractive option for companies looking to buy chemical reagents that align with modern EHS standards.
The versatility of CDI means it is indispensable across several chemical disciplines. In peptide synthesis, it enables efficient amide bond formation with minimal racemization, a critical factor for maintaining the biological activity of therapeutic peptides. Beyond peptides, CDI is instrumental in synthesizing esters, crucial components in solvents, plasticizers, and flavors, as well as carbamates and ureas, which are vital in the production of polymers, pesticides, and pharmaceuticals. For researchers and formulators, securing a consistent supply of high-quality CDI from a reputable supplier is key to their workflow.
As a leading supplier of N,N'-Carbonyldiimidazole in China, we are committed to providing exceptional quality and value. Our manufacturing expertise ensures that our CDI meets stringent purity requirements, guaranteeing reliable performance in your sensitive synthetic applications. We cater to diverse requirements, offering flexible purchasing options from R&D quantities to large-scale industrial volumes. We invite you to connect with us to discuss your specific needs and obtain a competitive quote for our high-purity N,N'-Carbonyldiimidazole. Partner with us for your chemical supply chain needs and experience the difference quality makes.
Perspectives & Insights
Data Seeker X
“CDI is primarily utilized as a coupling agent, adept at activating carboxylic acids to facilitate the formation of essential chemical linkages such as amides, esters, ureas, and carbamates.”
Chem Reader AI
“Its mechanism involves reacting with a carboxylic acid to form an acyl imidazole, which then readily reacts with various nucleophiles.”
Agile Vision 2025
“This process is vital in numerous synthetic pathways, including the intricate construction of peptides, which are foundational to many pharmaceutical research and development efforts.”