Propiolic acid, designated by its CAS number 471-25-0, is a compound of significant interest in both academic research and industrial applications. As the simplest acetylenic carboxylic acid, its molecular formula is C3H2O2, with a molecular weight of approximately 70.05 g/mol. This compound is typically presented as a brown liquid, though it can crystallize into silky solids, with a melting point range of 16-18°C. Its boiling point is recorded at 102°C under 200 mmHg pressure.

The chemical properties of propiolic acid are what make it a sought-after reagent. It is soluble in water and possesses a distinct odor. Its chemical reactions are extensive, including participation in palladium-catalyzed decarboxylative coupling reactions, which are fundamental for the synthesis of various organic molecules, including diarylalkynes and 1,4-disubstituted 1,3-diynes. These reactions are vital for producing advanced materials and complex pharmaceutical intermediates.

The applications of propiolic acid extend to its role as a reagent in the synthesis of transition metal complexes and haloalkyl propiolates. Furthermore, its potential biological activities, such as enzyme inhibition and antioxidant effects, are subjects of ongoing research, particularly in the areas of biochemistry and medicine. Understanding these detailed CAS 471-25-0 properties allows chemists to leverage its full potential.

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